2020
DOI: 10.1007/s11033-020-05939-w
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Royal jelly attenuates gastric mucosal injury in a rat ethanol-induced gastric injury model

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Cited by 15 publications
(14 citation statements)
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“…Unfortunately, owing to their significant side effects, such as gynecomastia, hypoacidity, impotence, osteoporotic bone fracture, hypergastrinemia, and cardiovascular disease risks, these medications are facing serious challenges [7][8][9]. Therefore, natural products with a broad range of biological actions, improved efficacy, and safety are required to replace chemical drugs [10,11].…”
Section: Introductionmentioning
confidence: 99%
“…Unfortunately, owing to their significant side effects, such as gynecomastia, hypoacidity, impotence, osteoporotic bone fracture, hypergastrinemia, and cardiovascular disease risks, these medications are facing serious challenges [7][8][9]. Therefore, natural products with a broad range of biological actions, improved efficacy, and safety are required to replace chemical drugs [10,11].…”
Section: Introductionmentioning
confidence: 99%
“…36 The high expression of IL-6 during inflammation may be an important cause of ethanol-induced gastric mucosal injury, 21 and IL-1⊎ contributes to the development of gastric mucosal injury by promoting the accumulation of neutrophils. 37 There was a negative correlation between grain consumption and the IL-6 level. 38 Quinoa is rich in anti-inflammatory phytochemicals, and so it has potential anti-inflammatory and protective effects.…”
Section: Discussionmentioning
confidence: 94%
“…It triggers cytotoxicity, apoptosis and acute‐phase responses in the pathological process, and is involved in the occurrence of inflammatory lesions and damage in gastric tissue 36 . The high expression of IL‐6 during inflammation may be an important cause of ethanol‐induced gastric mucosal injury, 21 and IL‐1 β contributes to the development of gastric mucosal injury by promoting the accumulation of neutrophils 37 . There was a negative correlation between grain consumption and the IL‐6 level 38 .…”
Section: Discussionmentioning
confidence: 99%
“…Based on previous studies, the gastric ulcer index has become an important indicator to assess treatment efficiency [19,20]. Previous studies suggest that the ulcer index of the stomach was decreased significantly through BGF pretreatment for seven days, providing direct evidence of BGF inhibited gastric injury.…”
Section: Discussionmentioning
confidence: 99%