2018
DOI: 10.2807/1560-7917.es.2018.23.19.17-00381
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Rubella infection in pregnancy and congenital rubella in United Kingdom, 2003 to 2016

Abstract: Rubella vaccination has been included in the United Kingdom’s (UK) routine childhood schedule for nearly 30 years. The UK achieved World Health Organization (WHO) elimination status in 2016 and acute rubella infections are rare. In the period 2003–16, 31 rubella infections in pregnancy (0.23 per 100,000 pregnancies) were identified through routine surveillance, of which 26 were in women who were born abroad. Five of the 31 rubella infections led to congenital rubella syndrome in the infant and three had confir… Show more

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Cited by 20 publications
(23 citation statements)
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“…Also, we observed an alarmingly low rate of anti-rubella seropositivity in the small specimen of serologically tested pregnant refugees: only 44% of the expecting mothers had protective anti-rubella IgG-levels. Even though seroprevalences do not necessarily reflect immunity acquired by vaccination, this observation is in line with previous reports by us and others and illustrates a significant gap in rubella immunity in young female refugees [ 16 , 17 , 33 , 34 , 35 ].…”
Section: Discussionsupporting
confidence: 91%
“…Also, we observed an alarmingly low rate of anti-rubella seropositivity in the small specimen of serologically tested pregnant refugees: only 44% of the expecting mothers had protective anti-rubella IgG-levels. Even though seroprevalences do not necessarily reflect immunity acquired by vaccination, this observation is in line with previous reports by us and others and illustrates a significant gap in rubella immunity in young female refugees [ 16 , 17 , 33 , 34 , 35 ].…”
Section: Discussionsupporting
confidence: 91%
“…The introduction of the rubella vaccine into the routine immunization schedule is essential for reducing the burden of morbidity and mortality due to this disease. 14 The fight against CRS requires a multidisciplinary team which provides the preventive and curative components. 15 The behavior of healthcare providers is one of the factors that determine the quality of the care they provide.…”
Section: Discussionmentioning
confidence: 99%
“…Due to the often asymptomatic course of some viral infections, ineffectiveness or inability to apply treatment and in the case of many viruses lack of vaccines, an obstacle to reducing the number of viral infections is primarily a lack of public awareness of preventive measures that can be taken to prevent them [13]. By implementing a vaccination programme against the rubella virus, the effective protection of women of childbearing age has been successfully achieved, and thus the cases of congenital rubella syndrome and the number of miscarriages and premature births as a result of RBV infection during pregnancy, have been successfully reduced [14]. Unfortunately, in the case of other viral infections, which may cause congenital infections, such as CMV, HSV, parvovirus, no effective immunization strategy is available.…”
Section: Discussionmentioning
confidence: 99%