Rumen phosphorus metabolism in sheep

Dias, R. S.; López, Secundino; Silva, T. S.; Pardo, René Mauricio Patiño; Filho, José Carlos Silva Camargo; Vitti, D. M. S. S.; Kebreab, E.

doi:10.1017/s0021859609008673

Cited by 10 publications

(9 citation statements)

References 29 publications

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“…Ruminants may be different because they recycle P into the rumen via saliva to provide P to their micro‐organisms (Dias et al., ; Engelhardt & Breves, ) and therefore might not need to remove Ca from the digestive tract; their faeces typically contain higher Ca concentrations and Ca/P ratios than those of hindgut fermenters (Schryver et al., ). In addition, in ruminants, renal P excretion shows considerable interindividual variation that appears to be higher than in other species (Taube, ; Taube, Rohn, Kreienbrock, & Kamphues, ).…”

Section: Introductionmentioning

confidence: 99%

A comparative meta‐analysis on the relationship of faecal calcium and phosphorus excretion in mammals

Böswald

Dobenecker

Clauss

et al. 2017

Animal Physiology Nutrition

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SummaryTo investigate the relationship between faecal calcium (Ca) and phosphorus (P) excretion in different mammalian species, a meta-analysis on digestibility data derived from the literature was conducted. Seventy-three studies on carnivores, omnivores, large and small hindgut fermenters, ruminants and hippos (a total of 21 mammalian species, precondition for inclusion dietary Ca/P ratio 1.5/1 -3.0/1) were analysed for Ca and P digestibility. Dietary Ca/P ratios were lower than faecal Ca/P ratios in carnivores, omnivores, ruminants and hippos. In hindgut fermenters, dietary Ca/P ratios were higher than faecal Ca/P ratios, indicating higher intestinal Ca absorption in these species. In all species investigated, there was a significant positive relationship between Ca intake and faecal Ca excretion and between P intake and faecal P excretion. In the biologically relevant range, these equations predicted lower faecal Ca losses in hindgut fermenters than ruminants, for faecal P vice versa. In all species, faecal Ca and P excretion correlated significantly. In carnivores, this highly linear correlation was exceptionally strong (R² = .92). Yet, the linearity of the correlation was questionable in omnivores and ruminants. Possibly, the strong linear correlation of faecal Ca and P excretion in carnivores is due to the formation of insoluble Ca/P complexes in their relatively short and simple gastrointestinal tract. Another hypothesis is that in carnivores, Ca homeostasis relies on modifying bone turnover to a higher degree than on changes in intestinal Ca absorption. For the formation of bone matrix, a constant ratio of Ca and P absorption is of advantage. K E Y W O R D Sbone turnover, calcium, comparative, digestibility, phosphorus | INTRODUCTIONIn a meta-analysis on calcium (Ca) and phosphorus (P) intake vs. faecal excretion in dogs and cats, Mack, Alexander, Morris, Dobenecker, and Kienzle (2015) observed a close linear relationship between faecal Ca and P excretion (R² = .94 in dogs), regardless of the Ca/P ratio and the source of Ca and P in the food. A possible explanation could be the formation of insoluble Ca/P complexes. Whether similar close relationships can be observed in mammalian species other than domestic carnivores has, to our knowledge, not been investigated. A comparative investigation of the relationship between faecal Ca and P excretion may help to understand differences and similarities between species. One hypothesis is that the regression equation of faecal Ca and P excretion reflects the intestinal formation of insoluble Ca/P complexes. In chickens, a constant ratio of intestinal Ca/P has been found (Hurwitz & Bar, 1971) and interpreted as the formation of insoluble Ca 3 (PO 4 ) 2 (Humer, Schwarz, & Schedle, 2015). The atomic weight ratio of Ca to P in this complex is 2 to 1, which should be represented in the regression equation of faecal Ca and P excretion if the complex actually is a major determinant of mineral excretion.Another assumption is that microbial activity in the gastrointestina...

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Section: Introductionmentioning

confidence: 99%

A comparative meta‐analysis on the relationship of faecal calcium and phosphorus excretion in mammals

Böswald

Dobenecker

Clauss

et al. 2017

Animal Physiology Nutrition

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“…As the salivary glands can concentrate P i from plasma by a factor of up to 16, approximately 50% of rumen P i can origin from saliva (Breves & Schröder, 1991; Read, Engels, & Smith, 1986). Although a tight correlation could be demonstrated between blood plasma and saliva P i concentrations (Mañas‐Almendros et al., 1982; Valk, Šebek, & Beynen, 2002), some controversy exists as to whether salivary P i secretion is regulated in order to maintain P i homeostasis or to ensure rumen microbial growth (Dias et al., 2009; Kebreab et al., 2005). As expected, we found a reduction in both salivary and rumen P i concentrations with dietary P restriction (Table 3), but a positive linear correlation between serum and salivary P i was only revealed in the control group (Figure 4).…”

Section: Discussionmentioning

confidence: 99%

Dietary phosphorus restriction affects bone metabolism, vitamin D metabolism and rumen fermentation traits in sheep

Köhler

Grünberg

Schnepel

et al. 2020

Animal Physiology Nutrition

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Homeostasis of calcium (Ca) and phosphate (Pi) is maintained by a concerted interplay of absorption and reabsorption via the gastrointestinal tract and the kidney and by storage and mobilization from the bone regulated mainly by parathyroid hormone (PTH), 1,25‐dihydroxycholecalciferol and calcitonin. The present study aimed at characterizing the effects of dietary P restriction on bone, vitamin D metabolism and rumen fermentation traits reflecting the endogenous P cycle maintaining the ruminal P supply for microbial metabolism. The experiments were done in eleven female, non‐pregnant, non‐lactating four‐ to nine‐year‐old Black Headed Mutton sheep allotted to two feeding groups: "P‐restricted" (0.11% P/kg DM and 0.88% Ca/kg DM) and "Control" (0.38% P/kg DM and 0.88% Ca/kg DM). Dietary P restriction did not lead to hypophosphataemia, probably due to a compensation by bone mobilization, demonstrated by increased serum concentrations of a resorption marker and altered gene expression in bone tissue. In addition, the RNA expression of fibroblast growth factor 23, a bone‐derived factor involved in the regulation of vitamin D metabolism, was significantly reduced with dietary P restriction. Furthermore, several genes related to vitamin D metabolism and plasma concentrations of 1,25‐(OH)2D were associated with serum concentrations of phosphate (Pi). In the parotid gland, the expression of the Pi transporter NaPi2b was negatively associated with serum Pi and positively with parathyroid PTH expression. Although Pi concentrations in saliva and the gastrointestinal tract were significantly reduced, we found no adverse effects of the P‐restricted ration on the production of short chain fatty acids, but slight differences in the production of butyrate as well as its relationship to rumen Pi and ammonia concentrations that might indicate an impact on ruminal fermentation.

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“…In ruminants, the amount of mineral excreted varies according to the type of diet. The amount and the source of phosphorus used in the diet also affect the kinetics of the mineral in the body [39,40]. The age of the animal can influence the use of dietary phosphorus, since it has been observed that young animals have higher absorption efficiency [41].…”

Section: Discussionmentioning

confidence: 99%

Effect of Mineral Supplementation on the Macromineral Concentration in Blood in Pre- and Postpartum Blackbelly Sheep

Tapia

Leib

Marini

et al. 2020

Animals

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The objective of this study was to determine the effect of mineral supplementation on the serum concentration of calcium, phosphorus, and magnesium in pre- and postpartum Blackbelly sheep throughout three successive lambing periods under free grazing conditions in the Ecuadorian Amazon Region. The field work was carried out between January 2015 and February 2018 using 20 Blackbelly sheep belonging to the Centre for Research, Postgraduate Studies and Conservation of Amazon Biodiversity, Ecuador. The flock was randomly divided into two groups: Group 1 (G1) was fed with forage plus a supplementation (Pecutrin® Mineral supplement plus vitamins A, D3, and E. Bayer HealthCare) and Group 2 (G2) was fed only with forage without mineral supplementation. Three blood samples from the coccygeal vein were taken from each sheep 30 days before lambing, 30 days after, and 60 days after lambing. Concerning the average of calcium, significant differences were found at different times inside each group and also between them (p < 0.0001 in both cases). As for the phosphorus, significant differences were found between the means of the groups for all times from 30 days after the second lambing season (p < 0.05). It was observed that the groups differed significantly in terms on the average of magnesium (considering a significance level of 0.05) 30 days before the first lambing and at all times measured from the 30 days after the second lambing (p < 0.005). In this study, we showed that Blackbelly sheep raised under free grazing conditions in the Ecuadorian Amazon Region had very low serum calcium values, and supplementation was unable to improve them. Meanwhile, phosphorus and magnesium levels were below the required values, but after supplementation, they exceeded the minimum threshold. Mineral supplementation in the rearing of sheep in grazing systems is necessary during the entire production cycle, but it must be done taking into account the soil–plant–animal relationship specifically for the Amazonian Region systems.

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Rumen phosphorus metabolism in sheep

Cited by 10 publications

References 29 publications

A comparative meta‐analysis on the relationship of faecal calcium and phosphorus excretion in mammals

A comparative meta‐analysis on the relationship of faecal calcium and phosphorus excretion in mammals

Dietary phosphorus restriction affects bone metabolism, vitamin D metabolism and rumen fermentation traits in sheep

Effect of Mineral Supplementation on the Macromineral Concentration in Blood in Pre- and Postpartum Blackbelly Sheep

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