Rumex nepalensis Spreng. Rumex hastatus D. Don Rumex longifolius DC. Polygonaceae

Sharma, Grinsun; Poudel, Prakash; Thapa, Raj Kumar; Lamichhane, Santosh; Poudel, Hem Raj; Devkota, Hari Prasad; Kunwar, Ripu M.; Jan, Hammad Ahmad; Sher, Hassan; Rahman, Ikram Ur; Abbasi, Arshad Mehmood; Bussmann, Rainer W.; Paniagua-Zambrana, Narel Y.

doi:10.1007/978-3-030-45597-2_209-1

Cited by 2 publications

(2 citation statements)

References 64 publications

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“…(9) The plant grows in all seasons of the year, and has broad roots, upright stems, with basal leaves up to 10 cm long. (10) Extracts of R. nepalensis are claimed to exhibit anti-ulcer (11) , abortifacient (8), antioxidant and anti-inflammatory (12), hypoglycemic and analgesic (13), antiplasmodial and antimicrobial (14), and antimalarial activities. (15) These investigations have led to the separation of secondary phytochemicals from the plant such as alkaloids, flavonoids, phenolic compounds, and glycosides.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Diuretic Activities of 80% Methanol Leaf Extract and Solvent Fractions ofRumex nepalensisin Mice

Tafesse,

Asrie,

Belete

2023

Preprint

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BackgroundThe leaf ofRumex nepalensishas historically been employed to treat urinary retention and as a diuretic. Despite these assertions, there has been very little research addressing the diuretic effect of the leaves ofR. nepalensis. Therefore, this study was done to examine the diuretic properties of R. nepalensis leaves.MethodsCold maceration with 80% methanol was used to extract the coarsely powdered leaves ofR. nepalensis. The extract was separated using increasing polarity solvents, beginning with n-hexane, ethyl acetate, and water. Mice were split into sections to test the plant’s diuretic properties. The negative control groups were given either distilled water or 2% tween 80; the positive control groups were given furosemide (10 mg/kg); and the test groups were given the 80% methanol extract and solvent fractions orally at dosages of 100, 200, and 400 mg/kg. The urine volume was determined, and urine analysis was performed on each extract.ResultsAt dosage levels of 200 mg/kg and 400 mg/kg, the 80% methanol extract, ethyl acetate fraction, and aqueous fraction all produced substantial diuresis (p<0.001) as compared to the negative control. Similarly, mice given the 80% methanol extract, ethyl acetate fraction, and aqueous fraction demonstrated substantial natriuresis (p<0.001) and kaliuresis (p<0.001) at dosages of 200 mg/kg and 400 mg/kg, respectively, in comparison to the negative control.ConclusionThe diuretic activity ofR. nepalensiswas significantly seen in the 80% methanol extract, ethyl acetate, and aqueous fractions, which corroborated the plant’s traditional use.

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Section: Introductionmentioning

confidence: 99%

Evaluation of the Diuretic Activities of 80% Methanol Leaf Extract and Solvent Fractions ofRumex nepalensisin Mice

Tafesse,

Asrie,

Belete

2023

Preprint

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show abstract

“…Ethnobotanical surveys show the plant to have a lot of nutritional and therapeutic importance. Its leaves are used as vegetable and consumed as both cooked and uncooked ( Sharma et al., 2021 ), as prickles ( Sinica, 2013 ) and as flavoring agent ( Sahreen et al., 2014a , Sahreen et al., 2014b ). In ethnomedicine, it is reported to be used to treat many ailments including rheumatism, skin diseases, piles as well as the sexually transmitted diseases ( Sahreen et al., 2014a , Sahreen et al., 2014b ).…”

Section: Introductionmentioning

confidence: 99%

Modelling and optimization of polyphenol and antioxidant extraction from Rumex hastatus by green glycerol-water solvent according to response surface methodology

Anis

Ahmed

2022

Heliyon

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Rumex nepalensis Spreng. Rumex hastatus D. Don Rumex longifolius DC. Polygonaceae

Cited by 2 publications

References 64 publications

Evaluation of the Diuretic Activities of 80% Methanol Leaf Extract and Solvent Fractions ofRumex nepalensisin Mice

Evaluation of the Diuretic Activities of 80% Methanol Leaf Extract and Solvent Fractions ofRumex nepalensisin Mice

Modelling and optimization of polyphenol and antioxidant extraction from Rumex hastatus by green glycerol-water solvent according to response surface methodology

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