Ruminant Placental Adaptation in Early Maternal Undernutrition: An Overview

Toschi, Paola; Baratta, Mario

doi:10.3389/fvets.2021.755034

Cited by 5 publications

(2 citation statements)

References 140 publications

(235 reference statements)

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“…It is believed that IGF-1 causes efficient nutrient usage rather than increased placental blood flow or nutrient transfer to the fetus. The role of hormones in nutrient transport across the placenta was reviewed, while IGF-1 regulates glucose uptake by stimulating GLUT1 receptor expression in the placenta [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Serum insulin-like growth factor-1 and leptin concentrations in Black Bengal goats at different ages and gestation periods and their relationship to kid growth performance

Buranakarl,

Chamsuwan,

Nuntapaitoon

2024

Vet World

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Background and Aim: The impact of maternal hormone concentration on kid growth performance in relation to insulin-like growth factor 1 (IGF-1) and leptin is minimal. This study examined IGF-1 and leptin levels at varying ages and gestation periods for their correlation with Black Bengal goat kids’ growth during the preweaning phase. Materials and Methods: Blood samples were collected from 43 dams with different reproductive cycles and 28 prepubertal goats to measure serum concentrations of IGF-1 and leptin. Among dams, both hormones were investigated in different age ranges (<2, 2–3, 3–4, and >4 years old) and reproductive cycles (non-pregnancy, early gestation (1–50 days), mid-gestation (51–100 days), late gestation (101–135 days), and the last 15 days before delivery). After delivery, 65 kids from 34 dams were weighted weekly for 8 weeks to calculate average daily weight gain (ADG) at 0–4 weeks (ADG0–4 W) and 4–8 weeks (ADG4–8 W) and growth performance, including weight (W), height (H), length (L), chest girth (C) measured at birth (W0, H0, L0, and C0) and at 10 weeks of age (W10, H10, L10, and C10) were related to hormone serum concentrations in their dams at different gestation periods including the last 15 days before delivery. Results: Dams had higher mean serum IGF-1 (p < 0.001) and leptin (p < 0.05) than prepubertal goats. Dams at late gestation had higher IGF-1 concentrations than those at early and mid-gestation and during the last 15 days before delivery. However, it was consistent with non-pregnant goats. The kid’s growth performance correlated positively with IGF-1 concentration, which was collected in the last 15 days before delivery. Multivariate analysis showed that ADG0–4 W was higher in kids born from dams with high IGF-1 than those with low IGF-1 measured during the last 15 days of delivery, whereas leptin tended to have a similar effect. Conclusion: Serum IGF-1 and leptin concentrations of dams measured during the last 15 days before delivery were associated with kid’s growth during the preweaning period. Keywords: Black Bengal goat, growth performance, insulin-like growth factor 1, leptin.

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Section: Discussionmentioning

confidence: 99%

Serum insulin-like growth factor-1 and leptin concentrations in Black Bengal goats at different ages and gestation periods and their relationship to kid growth performance

Buranakarl,

Chamsuwan,

Nuntapaitoon

2024

Vet World

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“…In mammals, the placenta is the first organ to form during embryonic development; it exchanges respiratory gases, nutrients, and waste between the maternal and fetal systems throughout pregnancy [1,2]. Therefore, proper placentation is critical for successful pregnancy [1]. In cattle, different growth patterns have been reported between the placenta and fetus.…”

Section: Introductionmentioning

confidence: 99%

Differences in daily milk production during early pregnancy alter placental characteristics and neonatal metabolic amino acid levels in dairy cows

Kawashima

2023

J. Reprod. Dev.

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We investigated the effects of differences in milk production during early pregnancy on placental characteristics at full term, calf birth weights, and their metabolic status. Thirty-four Holstein cows were categorized into three groups (Low, n = 9; Middle, n = 16; High, n = 9) based on the quartile of average daily 4% fat-corrected milk production during early pregnancy. The High group showed higher milk component production than the other groups (P < 0.05) during early and mid-pregnancy.Although most placental characteristics did not differ significantly among the groups, cows in the High group had larger individual cotyledons and fewer medium-sized cotyledons than those in the Low group (P < 0.05). Plasma amino acid concentrations of calves in the Low and High groups were significantly 2 higher than those of calves in the Middle group, although calf birth weights were similar among the groups. Furthermore, cows in the Low group had longer dry periods than those in the High (P = 0.004) and Middle (P = 0.058) groups. This suggests that cows in the Low group may have provided more amino acids to the fetus because of low lactation and long dry periods. Conversely, cows in the High group required more energy for lactation during early pregnancy, which can reduce nutrient availability to the placenta and fetus; however, increasing individual cotyledonary sizes during late pregnancy may ensure that the same amounts of amino acids as those in cows in the Low group are supplied to the fetus, recovering the birth weights.

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Effect of birth rank, and placentome subtype on expression of genes involved in placental nutrient transport in sheep

et al. 2023

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Ruminant Placental Adaptation in Early Maternal Undernutrition: An Overview

Cited by 5 publications

References 140 publications

Serum insulin-like growth factor-1 and leptin concentrations in Black Bengal goats at different ages and gestation periods and their relationship to kid growth performance

Serum insulin-like growth factor-1 and leptin concentrations in Black Bengal goats at different ages and gestation periods and their relationship to kid growth performance

Differences in daily milk production during early pregnancy alter placental characteristics and neonatal metabolic amino acid levels in dairy cows

Effect of birth rank, and placentome subtype on expression of genes involved in placental nutrient transport in sheep

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