Rupture of the Spleen in Amyloidosis

Abstract

tained at the time of bladder-washout localization. However, investigators using voided urine specimens must be aware of false-positive results from contamination with bacteria originat¬ ing from feces.3 False-positive find¬ ings can also occur if a negative control is not always studied concomitantly with the unknown. Nonspecific fluorescence can result in a falsepositive ACB test. Perhaps antibody present in the urine can attach to organisms in the bladder and give false-positive results. However, we have not observed this in our patient population.Regardless of the reasons for the disparity, further studies are needed to determine the usefulness of the ACB test in all categories of patients with urinary tract infection. At pres¬ ent, we do not think the test should be used routinely in hospital laborato¬ ries, but should be available for women in epidemiologic and thera¬ peutic studies so that the contribution of the site of infection to course of the illness may be evaluated.

Spontaneous rupture of the spleen in AL amyloidosis

“…In a review of the literature, we have been able to identify 17 cases of splenic rupture associated with amyloidosis reported since 1948 [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28]. Although this number does not define the actual incidence of spontaneous rupture of the spleen in amyloidosis, it suggests the splenic rupture is a rare complication in this disease.…”