Ruptured cystic mesenchymal hamartoma: An unusual cause of neonatal ascites

George, Joseph C.; Cohen, Mervyn D.; Tarver, Robert D.; Rosales, Remedios

doi:10.1007/bf02015467

Cited by 26 publications

(5 citation statements)

References 2 publications

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“…There are isolated case reports of MHL causing pulmonary hypertension, vascular steal and thrombocytopenia [33], perinatal tumor rupture with ascites [34], obstructive jaundice [10], and fatal bleeding into the tumor after birth trauma [35]. In the newborn, the tumor may expand rapidly to cause life-threatening abdominal distension [36].…”

Section: Presentationmentioning

confidence: 99%

Mesenchymal hamartoma of the liver: a systematic review

Stringer

Alizai

2005

Journal of Pediatric Surgery

182

189

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Section: Presentationmentioning

confidence: 99%

Mesenchymal hamartoma of the liver: a systematic review

Stringer

Alizai

2005

Journal of Pediatric Surgery

182

189

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“…There are also several cases of neonatal death, when HMH was only discovered immediately after birth [20,[23][24][25] . This poor outcome was confirmed by a recent review of fetal and neonatal hepatic tumors [26] .…”

Section: Discussionmentioning

confidence: 99%

Mesenchymal Hamartoma of the Liver: A Benign Tumor with Deceptive Prognosis in the Perinatal Period

Cornette¹,

Festen

Hoonaard

et al. 2009

Fetal Diagn Ther

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This article reports a case of perinatal mesenchymal hepatic hamartoma and reviews the literature on the subject. A fetus presented with polyhydramnios and a large multiloculated cystic abdominal mass at 33 weeks of gestation. The ultrasound appearance was most consistent with a mesenteric cyst. Prenatal drainage was considered, due to the size of the lesion. However, a conservative management was opted for. A female infant was born at 35 weeks by classical cesarean section. The immediate postnatal period was characterized by hemodynamic instability. Laparotomy revealed a pedunculated mesenchymal hamartoma of the liver, which could not completely be resected. The infant had an uneventful postoperative recovery and is doing well at 6 months of age. Hepatic mesenchymal hamartoma are rare benign tumors. Most cases are detected in early childhood. They usually present as a cystic rapidly growing abdominal mass. Prenatal diagnosis remains challenging. In children diagnosed in the perinatal period, the outcome seems worse and determined by the compressive effect of the mass.

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“…Hepatic mesenchymal hamartoma, fi rst reported by Edmondson in 1956 [7] , is a rare hepatic tumor of infancy that presents as a painless abdominal mass and distension [5,16] . The majority of cases are detected incidentally, but other presentations include respiratory distress in the newborn [20] , high-output cardiac failure [18] , peri-natal tumor rupture with ascites [9] , and obstructive jaundice [8] . Multimodal imaging demonstrates a multi-loculated cystic tumor with a variable amount of solid tissue.…”

Section: Discussionmentioning

confidence: 99%