Ruthenium‐ and Rhodium‐Catalyzed Strain‐Driven Cleavage and Reconstruction of the C–C Bond

Abstract

Abstract:The synthesis of new functional organic molecules that cannot be obtained by a simple combination of conven-

Capturing the Organic Species Derived from the C–C Cleavage and in Situ Oxidation of 1,2,3,4-Tetra(pyridin-4-yl)cyclobutane by [CuCN]n-Based MOFs

“…1−3 In spite of the thermodynamic stability of the C−C bonds, there has been a growing interest in their catalytic activation and transformation. 4,5 The past decades have witnessed a significant progress in activating the C−C bonds of strained three-and four-membered rings. 2 Cyclobutanes are essential structural motifs for numerous unique organic transformations.…”

Development and Mechanistic Study of Quinoline-Directed Acyl C–O Bond Activation and Alkene Oxyacylation Reactions

“…The field of catalytic C–C bond activation is rapidly growing and has been the subject of several recent reviews and books . With the notable exception of nitriles, much of the recent work in this area has focused on strained ring systems . Our early efforts focused on metal catalyzed activation of unstrained C–C bonds to trigger the carboacylation of alkenes .…”

Metal-Catalyzed Carbon–Carbon Bond Cleavage of Unstrained Alcohols

“…Over the recent decades, C–C bond cleavage has become an active field in research, and several reviews about the activation of small rings and unstrained systems highlight the recent achievements in this field. ,,− This review focuses on catalytic C–C bond cleavage reactions of unstrained alcohols (Figure a). Beyond the scope of this review are reactions involving C–C oxidative additions (Figure b), which have been reviewed elsewhere. ,,,,,− Likewise, retro-allylation reactions (Figure c) and cleavage of alcohols driven by the release of ring strain (Figure d) − will not be covered herein. Moreover, radical-induced fragmentations and related proton-coupled electron transfer (PCET) processes will also not be discussed, as they have been reviewed recently (Figure e). , Notably, other strategies in C–C bond activation are discussed in other reviews in this thematic issue.…”