Abstract:In this article, some of the ruthenium‐catalyzed directed and nondirected CH activation led functionalizations, such as alkylation, alkenylation, arylation, and amidation, which have been elegantly applied in the synthesis of various natural products and active pharmaceutical intermediates (API), has been described. Along with this, the novel approaches like the transient directing group (TDG) and chiral transient directing group (CTDC) aided asymmetric synthesis of the key intermediates employed in a total s… Show more
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