2023
DOI: 10.1155/2023/6820338
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Rutin‐Rich Flavonoid Subfraction of Annona senegalensis Mitigates Trypanosoma brucei brucei Infection and Hematobiochemical Changes in Infected Mice

Abstract: Trypanosomiasis is an important but neglected tropical diseases which continues to cause morbidity and mortality on a large scale in sub-Saharan Africa. In the present study, the aqueous leaf extract, flavonoid fraction, and subfractions of the flavonoid from A. senegalensis leaves were evaluated for their antitrypanosomal activities, effects on some hematological parameters, and some liver-based enzymes in mice infected with Trypanosoma brucei brucei. Mice treated with aqueous extract at a concentration range… Show more

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