We propose a mechanism of ground-state blockade between two N -type Rydberg atoms in virtue of Rydbergantiblockade effect and Raman transition. Inspired by the quantum Zeno effect, the strong Rydberg antiblockade interaction plays a role in frequently measuring one ground state of two, leading to a blockade effect for double occupation of the corresponding quantum state. By encoding the logic qubits into the ground states, we efficiently avoid the spontaneous emission of the excited Rydberg state, and maintain the nonlinear RydbergRydberg interaction at the same time. As applications, we discuss in detail the feasibility of preparing two-atom and three-atom entanglement with ground-state blockade in closed system and open system, respectively, which shows that a high fidelity of entangled state can be obtained with current experimental parameters.