S-cone ERGs elicited by a simple technique in normals and in tritanopes

Abstract

(1) clinical techniques used to isolate S-cone ERGs are appropriate; (2) there are at least two types of tritanope and in those we investigated, functional S-cones are probably displaced into the retinal periphery.

A detailed phenotypic description of autosomal dominant cone dystrophy due to a de novo mutation in the GUCY2D gene

“…S-cone ERGs were performed using a blue stimulus (445 nm, duration 5 ms, 80 cd/m 2 ) superimposed on a constant orange background (620 nm, 560 cd/m 2 ). 13 …”

Functional observations in vitamin A deficiency: diagnosis and time course of recovery

“…The S-cone system was examined using a 5 ms blue stimulus (80 cd/m 2 ) with an amber background (650 cd/m 2 ) at 1 Hz. 16 PERG was performed undilated. A black and white reversing checkerboard stimulus (rate 4.5/s, check size 45 0 , field size 151 Â 151) was used.…”

Clinical S-cone ERG recording with a commercial hand-held full-field stimulator

“…The Scones produce responses that are much smaller and considerably slower than L/M-cone responses, and it is difficult to isolate them without having them overwhelmed by the L/Mcone signals. A number of techniques have evolved for recording S-cone responses [2][3][4][5][6][7][8][9][10], but none of these protocols have found their way into routine clinical usage outside of the laboratory which initiated the technique. Our goal was to explore whether a clinical method for recording S-cone responses could be developed with commercially available Diagnosys instrumentation.…”