S1135 Post POEM Procedure Metabolic Changes: A Single Center Retrospective Analysis

Abstract

66 lesions were treated with uEMR-L in 51 patients. The mean size was 27.4 mm (range 15-60mm). The median submucosal injection volume was 7 ml (range 2-30ml, mean 9.2ml, SD 7.1). Complete resection was performed in 62/66 (94%) of the lesions. Of the incomplete resections, 2 were invasive adenocarcinoma, one extended into the appendiceal orifice, and one had extensive submucosal fibrosis. Ten of the lesions were removed en bloc, with mean size of 19.1 mm. Of the 62 lesions in which polypectomy was completed, 50 underwent surveillance examination a median of 200 days later. Only 2/50 polypectomy sites had residual polyp tissue which was resected endoscopically. One patient experienced delayed bleeding requiring admission. No other complications of bleeding, perforation, or unplanned admission were seen. (Table ) Conclusion: uEMR-L is a safe and effective technique for endoscopic mucosal resection of large nonmalignant colon polyps. This specific technique may preserve the benefits of underwater resection and serve as an entry point for endoscopists without previous experience in underwater EMR.