S134 Pre-EDIT: a randomised, feasibility trial of elastance-directed intra-pleural catheter or talc pleurodesis (EDIT) in the management of symptomatic malignant pleural effusion without obvious non-expansile lung

Malignant pleural effusion management: keeping the flood gates shut

“…Despite Lentz et al finding no benefit in the routine use of pleural manometry in predicting pain and complications during thoracentesis, it still may have value in predicting non-expandable lung and directing the clinician to an appropriate management pathway. A study specifically addressing whether pleural elastance assessment during therapeutic aspiration can successfully triage patients to either IPC or talc pleurodesis management is currently recruiting (7). A change in pleural elastance of >14.5 cm H20/L is used to denote negative pleural pressure and therefore non-expandable lung, which indicates that pleurodesis is less likely to be successful and insertion of an IPC would be recommended.…”