S2005 Colon Cancer Screening Practices At An HIV Outpatient Clinic: A Six Year Analysis

Ford, Ryan; Reid, Ashley; McMahon, M.; Patel, Ruchir P.; NeSmith, Elizabeth G.; Lennox, Jeffrey L.; Alhayani, Irfan; Obideen, Kamil; Wehbi, Mohammad

doi:10.1016/s0016-5085(08)61375-x

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A negative HIV viral load, normal CD4 cell count or being on HAART therapy does not appear to correlate with tumor prevention, tumor grade, tumor stage, or improved outcomes. This is because several factors predispose to the development of CRC in HIV patients such as microsatellite instability [ 7 ], HIV oncogenic proteins like the transactivator protein Tat [ 8 ], lifestyle factors (including tobacco and alcohol use), immune deficiency, chronic immune activation, and cytokine dysregulation [ 9 ]. The HIV oncogenic protein Tat has been reported to be responsible for the younger age of onset and aggressive behavior of colon cancer in HIV patients [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Colon Cancer in a Young Patient With HIV Infection: Is it Time for New Colon Cancer Screening Guidelines for HIV Patients?

Aziz,

Rashid

et al. 2023

Cureus

View full text Add to dashboard Cite

Patients with human immunodeficiency virus (HIV) infection have a higher prevalence of colonic neoplasms than the general population. In these patients, tumors develop at an earlier age, are diagnosed at more advanced stages, and have a dismal prognosis. Current guidelines recommend initiating colon cancer screening in HIV patients at the age of 45 which is consistent with screening age in the general population. We present a rare case of colon cancer diagnosed in an HIV-infected patient at a young age of only 34 years. Therefore, we recommend early screening for colon cancer in HIV patients than the general population.

show abstract