S2571 Cancer, the Colon, and an Inconspicuous Cause of Hematochezia

Abstract

help of endoloop placement followed by electrocautery-assistant resection and endoclip placement to close the resected area. The patient tolerated the procedure well without any consequence. Histopathology of the mass showed hyperplasia of Brunner's glands. Follow up endoscopy at 6 month revealed healed scar at the resected site without any endoscopic evidence of recurrence. Discussion: Brunner's gland hamartoma is an extremely rare duodenal tumor with an estimated incidence of 0.008%. The name arises from the Brunner's glands which are acinotubular glands that secrete alkaline fluid. The majority of patients are asymptomatic and have an incidental finding from the imaging or EGD. Patients commonly present with gastrointestinal bleeding and obstructive symptoms. EGD finding usually reveal a pedunculated mass 1-2cm in size located at duodenal bulb area consistent with Brunner's gland distribution. The diagnosis relies on endoscopic finding and imaging. The pathology of the tissue yields the definitive diagnosis. Often this polyp develops into thick wide stalk which may contains large blood vessel; EUS should be performed to assess the lesion as well and its vascularity. Endoloop placement prior to EMR should help prevent significant bleeding during the resection of the lesion as described in our case. Malignant potential has been reported to be extremely rare, but dysplastic changes and invasive carcinoma can be seen. (Figure). [2570] Figure 1. (A) Endoscopic view of a large pedunculated polyp at the duodenal bulb (B) Endosonographic view (white arrow) of the lesion at the duodenal bulb (C) Histopathology (H&E stain) shows hyperplasia of the Brunner's glands (D) Gross specimen of the mass measuring 3cm in size.