S2864 Massive Ascites as the Presenting Finding of Prolymphocytic T-cell Lymphoma

Gonzalez, Adalberto; Quevedo, Shany; Ahmed, Wesam; Zervos, Xaralambos

doi:10.14309/01.ajg.0000784988.58421.99

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“…Treating the underlying cause of non-cirrhotic portal hypertension is the mainstay of therapy currently. Patients can have massive ascites and spontaneous bacterial peritonitis with normal serologic workup allowing further investigation to identify the underlying cause, often malignancy [ 3 ]. Portal hypertension has been seen as a rare side effect of lymphomas or other myeloproliferative diseases, and it can be the first noticeable symptom to the patient in these cases.…”

Section: Discussionmentioning

confidence: 99%

“…The presence of massive ascites indicates a need for serologic workup revealing possible underlying malignancy and other conditions. Currently, the standard of treatment for non-cirrhotic portal hypertension is to treat the underlying cause [ 3 ]. Here, we present a rare case of ascites in a non-cirrhotic patient with underlying primary myelofibrotic disease.…”

Section: Introductionmentioning

confidence: 99%

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A Case of Non-cirrhotic Portal Hypertension in a Patient With Primary Myelofibrosis Disease

Mangal,

Jamil,

Nasser

et al. 2023

Cureus

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Idiopathic non-cirrhotic portal hypertension can emerge due to a varied spectrum of underlying and contributory factors, presenting in the form of abdominal distention as the initial symptom encountered. Often, a patient remains asymptomatic to the underlying cause and seeks medical care for their abdominal enlargement. As the portal hypertension continues to progress, ascites begins to develop due to a history of portal vein thrombosis being sufficient to increase splanchnic blood flow in a portal hypertensive pattern. We present a rare case of ascites in a non-cirrhotic patient due to portal vein thrombus with underlying myeloproliferative disease of primary myelofibrosis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%