S3590 Gastric GIST Presenting as Melena in a Hemodynamically Unstable Patient: A Case Report

Ekanayake, Lakmal S; Kumar, Ashwin; Triplett, Drew; Usman, Niaz

doi:10.14309/01.ajg.0000787892.64375.63

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“…[1][2][3][4][5] Mitotic count and tumor size are the main prognostic factors identified related to disease progression and survival, it is difficult to predict their biological behavior (benign / malignant), other prognostic morphological variables consider mucosal involvement, presence of necrosis, hypercellularity, cellular pleomorphism and anatomical localization. [1][2][3][4][5][6][7][8][9][10] We present the case of a patient with low gastrointestinal tract bleeding secondary to a gastrointestinal stromal tumor, as well as her diagnostic clinical approach in a third-level medical unit, as well as a brief review of the literature.…”

Section: Introductionmentioning

confidence: 99%

Low gastrointestinal tract bleeding secondary to low-grade gastrointestinal stromal tumor: case report

Caprielova¹,

Izaguirre²,

Chavarria³

et al. 2022

Int Surg J

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Gastrointestinal stromal tumors (GIST) are neoplasms of mesenchymal origin. We present the case of a patient with low gastrointestinal tract bleeding secondary to a gastrointestinal stromal tumor, as well as her diagnostic clinical approach in a third-level medical unit, as well as a brief review of the literature. The treatment of this neoplasm is surgical and ideally consists of complete resection with negative margins (R0). GISTs mostly affect patients between 4-6 decades of life with a slight predominance in women, with the stomach and small intestine being the most frequently affected organs. The immunohistochemical study shows positivity for c-KIT and CD34 in 100% and 63% of cases. The treatment is surgical which usually by maintaining free margins is curative

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