S77. Jumping to Conclusions and Facial Emotion Recognition Impairment in First Episode Psychosis Across Europe

Abstract

BackgroundJumping to conclusions (JTC) is a well-established reasoning and data gathering bias found in patients with psychosis even at illness onset (First Episode Psychosis, FEP). Preliminary work in this field focused primarily on the association with delusions, although jumping to conclusions has also been found in non-deluded schizophrenia patients after remission, and in individual with at risk mental state.Moreover, psychotic patients tend to show impairments in social cognition, struggling in identifying, processing and interpreting social clues. Deficits in facial emotion recognition (FER) – a key component of the construct – represent a well-replicated finding in schizophrenia. Furthermore, deficits in global facial affect recognition have been found in FEP with the same severity as at further stages, especially for anger recognition. The present study aims to measure JTC and FER bias in a sample of FEP recruited across 5 European countries, compared with healthy controls.MethodsData on JTC (Beads task 60:40), FER (Degraded Facial Recognition task – DFAR) and socio-demographics have been analysed in a sample of 643 FEP and 1019 population controls recruited as part as the EU-GEI study across UK, Netherlands, France, Spain, and Italy.IQ scores were used to exclude cases and controls with current IQ<70 (N=171) from JTC analysis and a score <41 (N=384) on the Benton Facial Recognition test for the analysis on DFAR. Logistic regression model was applied to predict case/control status using 1) JTC and 2) DFAR as predictive variables controlling for age, gender and country.ResultsWe showed that the presence of JTC bias varies across different countries both in cases (χ2=23.77 p<0.001) and controls groups (χ2=14.01 p=0.007).Logistic regression analyses revealed JTC to be a significant predictor of case/control status (Adj OR=1.88 CI 95%=1.43–2.29 p<0.001).As well as JTC, FER differed over Europe in both groups (FEP, total: F=17.37, p<0.001; neutral: F=12.4, p<0.001; happy: F=25.62, p<0.001; frightened: F=8.78, p<0.001; angry: F=5.48, p<0.001. Controls, total: F=23.06, p<0.001; neutral: F=21.72, p<0.001; happy: F=21.74, p<0.001; frightened: F=14.14, p<0.001; angry: F=12.49, p<0.001).Logistic regression analyses revealed all DFAR scores, except for happy emotions, to be negatively associated with case/control status (total: B=-.0182 p=0.001; neutral: B=-.054 p=0.003; happy: B=-.0196 p=0.2; frightened: B= -.065 p<0.001; angry: B=-.030 p=0.04).DiscussionThis study supports the evidence that 1) FEP patients are more likely to present JTC and FER impairments than controls; 2) cognition and social cognition might represent transcultural features of psychotic disorders.

The relationship between jumping to conclusions and social cognition in first-episode psychosis

“…That is, those people who have the JTC bias do not necessarily interpret the mental states of others more poorly than people who do not JTC. Our findings are consistent with previous findings by Woodward et al 32 . Using factor analysis, these authors found that JTC loaded in a different neurocognitive factor than ToM.…”

“…These results highlight the need for improving reasoning judgments that are involved in ER in people with FEP. The results are consistent with the previous findings by Tripoli et al 31,32 where it was observed that patients with FEP who displayed JTC recognised worse emotions globally compared with controls, which is especially important because few psychological treatments intervene in both constructs 36 . In this line, psychological interventions such as metacognitive training for psychosis (MCT) would be recommended, because it works with specific modules about ER and the importance of making judgments based on the search of sufficient evidence to do that 37,38 .…”

“…The relationship between JTC and SC has not been deeply examined. Tripoli et al 31,32 reported that people with FEP who have JTC tend to have low EP; in contrast, there was no association between JTC and AS 31 . Regarding the relationship between JTC and ToM, Takeda 33 and Woodward et al 34 did not find associations.…”