Sacchachitin, a novel chitin-polysaccharide conjugate macromolecule present in<i>Ganoderma lucidum</i>: Purification, composition, and properties

Chuang, Chao Ming; Wang, Hui Er; Chang, Chi Huang; Peng, Chiung Chi; Ker, Yaw Bee; Lai, Jing Erh; Chen, Kuan Chou; Peng, Robert Y.

doi:10.3109/13880209.2012.711840

Cited by 13 publications

(6 citation statements)

References 24 publications

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“…Examples are the Saccachitin reported by Su and colleagues and the Rhizochitin produced by Chien et al . , where the chitin extracted from mycelia is casted in membranes tested as skin substitute and for the growth of fibroblasts 49 , 50 or for its immunomodulatory activity 93 .…”

Section: Resultsmentioning

confidence: 99%

Advanced mycelium materials as potential self-growing biomedical scaffolds

Antinori

Contardi

Suarato

et al. 2021

Sci Rep

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Mycelia, the vegetative part of fungi, are emerging as the avant-garde generation of natural, sustainable, and biodegradable materials for a wide range of applications. They are constituted of a self-growing and interconnected fibrous network of elongated cells, and their chemical and physical properties can be adjusted depending on the conditions of growth and the substrate they are fed upon. So far, only extracts and derivatives from mycelia have been evaluated and tested for biomedical applications. In this study, the entire fibrous structures of mycelia of the edible fungi Pleurotus ostreatus and Ganoderma lucidum are presented as self-growing bio-composites that mimic the extracellular matrix of human body tissues, ideal as tissue engineering bio-scaffolds. To this purpose, the two mycelial strains are inactivated by autoclaving after growth, and their morphology, cell wall chemical composition, and hydrodynamical and mechanical features are studied. Finally, their biocompatibility and direct interaction with primary human dermal fibroblasts are investigated. The findings demonstrate the potentiality of mycelia as all-natural and low-cost bio-scaffolds, alternative to the tissue engineering systems currently in place.

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Section: Resultsmentioning

confidence: 99%

Advanced mycelium materials as potential self-growing biomedical scaffolds

Antinori

Contardi

Suarato

et al. 2021

Sci Rep

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“…An SC film comprised of 10∼50-μm fibers showed promising wound healing (Chao et al, 2020;Jones et al, 2020;Nawawi et al, 2019). The wound-healing effects of the chitin sheet from crab shell (Beschitin) and SC from G. tsuga were comparable (Chuang et al, 2013;Smelcerovic et al, 2008).…”

Section: Sacchachitin (Sc)mentioning

confidence: 99%

“…SC is a water-insoluble PS extracted from Ganoderma tsuga and Ganoderma lucidum (Chuang et al, 2013).…”

Section: Sacchachitin (Sc)mentioning

confidence: 99%

Fungal exopolysaccharides: Properties, sources, modifications, and biomedical applications

Hamidi

Okoro

Milan

et al. 2022

Carbohydrate Polymers

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“…Quinones are known to be oxidised derivatives of aromatic compounds and are often readily made from reactive aromatic compounds with electron-donating substituent such as catechols and phenols. Besides GTs, polypeptides, small peptides such as ganodermin, polysaccharide such as sacchachitin, and chitosan also possess antimicrobial and anti-parasitic properties (Mothana et al 2000; Wang & Ng 2006; Sanodiya et al 2009; Chuang et al 2013). Structures of antimicrobial and anti-parasitic compounds from Ganoderma sp.…”

Section: Antimicrobial and Anti-parasitic Bioactive Compoundsmentioning

confidence: 99%

Current and future perspective on antimicrobial and anti-parasitic activities of Ganoderma sp.: an update

Basnet

Liu

et al. 2017

Mycology

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Medicinal mushroom Ganoderma sp. is considered to be a key source for the production of therapeutic agents. Our current review indicates that a limited number (<19%; 79 out of >430) of isolated compounds have been tested and known to be active against several microorganisms and parasites. In this review, we aim to summarise all the antimicrobial and anti-parasitic works on Ganoderma sp. displayed on web of science, google scholar and endnote X7 from 1932 to August 2016. We further present and discuss the structure of active compounds against microorganisms and parasites. In addition, we also discuss the possible further research to identify lead compounds from Ganoderma sp. as a novel strategy to combat the potential global emergence of bad bugs and parasites.

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Sacchachitin, a novel chitin-polysaccharide conjugate macromolecule present inGanoderma lucidum: Purification, composition, and properties

Abstract: (2013) Sacchachitin, a novel chitinpolysaccharide conjugate macromolecule present in Ganodermalucidum: Purification, composition, and properties, Pharmaceutical Biology, 51:1, 84-95,

Cited by 13 publications

References 24 publications

Advanced mycelium materials as potential self-growing biomedical scaffolds

Advanced mycelium materials as potential self-growing biomedical scaffolds

Fungal exopolysaccharides: Properties, sources, modifications, and biomedical applications

Current and future perspective on antimicrobial and anti-parasitic activities of Ganoderma sp.: an update

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