2023
DOI: 10.1002/jsfa.12555
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Sacha inchi albumin delays skin‐aging by alleviating inflammation, oxidative stress and regulating gut microbiota ind‐galactoseinduced‐aging mice

Abstract: Background Sacha inchi albumin exhibits considerable functional activity with notable anti‐inflammatory and antioxidation properties, which could delay skin aging. However, its underlying mechanisms for delaying skin aging have not been elucidated. The aim of the present study was to investigate the anti‐skin‐aging effect of sacha inchi albumin (SIA) in d‐galactose induced‐aging mice. Results Sacha inchi albumin improved moisture content, collagen level, and the state of aged skin in rats. Sacha inchi albumin … Show more

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Cited by 4 publications
(3 citation statements)
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“…For instance, Ghaly et al noted a substantial rise in the Mucispirillum relative abundance in the gut microbiota of C57BL/6 mice after chronic UVB skin exposure [52], showing notable upregulation in mice with atopic dermatitis [54,55]. Furthermore, the gut microbiota of skin-aged rats induced by D-galactose showed elevated Mucispirillum relative abundance, which was effectively reduced by Sacha inchi albumin, ameliorating skin aging [56]. The relative abundance of Rikenellaceae_RC9_gut_group was notably upregulated in oleic acid-induced cutaneous acne mice, exhibiting a positive correlation with the inflammatory factor levels [57].…”
Section: Discussionmentioning
confidence: 99%
“…For instance, Ghaly et al noted a substantial rise in the Mucispirillum relative abundance in the gut microbiota of C57BL/6 mice after chronic UVB skin exposure [52], showing notable upregulation in mice with atopic dermatitis [54,55]. Furthermore, the gut microbiota of skin-aged rats induced by D-galactose showed elevated Mucispirillum relative abundance, which was effectively reduced by Sacha inchi albumin, ameliorating skin aging [56]. The relative abundance of Rikenellaceae_RC9_gut_group was notably upregulated in oleic acid-induced cutaneous acne mice, exhibiting a positive correlation with the inflammatory factor levels [57].…”
Section: Discussionmentioning
confidence: 99%
“…2 IPA is mainly composed of two glycosylated peptides containing all essential amino acids, with excellent emulsifying properties, solubility, easy digestion and absorption, delayed skin-aging and immunity improvement. [3][4][5] As a new high-quality plant protein source, IPA can meet the new demand for nutrition and function, and has great advantages and broad application prospects in the construction of food functional component delivery systems. 6 The utilization of IPA protein is currently low, and there are few related studies.…”
Section: Introductionmentioning
confidence: 99%
“…Inca peanut albumin (IPA) is a water‐soluble protein extracted and purified from the cake meal that accounts for 31% of the protein in the seeds, and 25% of the cake mass 2 . IPA is mainly composed of two glycosylated peptides containing all essential amino acids, with excellent emulsifying properties, solubility, easy digestion and absorption, delayed skin‐aging and immunity improvement 3‐5 . As a new high‐quality plant protein source, IPA can meet the new demand for nutrition and function, and has great advantages and broad application prospects in the construction of food functional component delivery systems 6 .…”
Section: Introductionmentioning
confidence: 99%