Sacha Inchi Oil (Plukenetia volubilis L.), effect on adherence of Staphylococus aureus to human skin explant and keratinocytes in vitro

González-Aspajo, Germán; Belkhelfa, Haouaria; Haddioui-Hbabi, Laïla; Bourdy, Geneviève; Deharo, Eric

doi:10.1016/j.jep.2015.06.009

Cited by 46 publications

(42 citation statements)

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“…Furthermore this result is similar to the findings of Maurer, Hatta‐Sakoda, Pascual‐Chagman, & Rodriguez‐Saona () who reported that Sacha inchi oil had a higher amount of polyunsaturated fatty acids (78.3–80.9 g/100g oil) than monounsaturated fatty acids (10.0–12.5 g/100 g oil), and saturated fatty acids (7.4–8.3 g/100g oil). Gonzalez‐Aspajo, Belkhelfa, Haddioui‐Hbabi, Bourdy, and Deharo () reported that Sacha inchi oil had 84% of polyunsaturated fatty acids, 9% of monounsaturated fatty acids, and 7% of saturated fatty acids. In addition, Zanqui et al () reported that Sacha inchi oil extracted by Soxhlet method had 75% of polyunsaturated fatty acids, 8.73% of monounsaturated fatty acids, and 9.13% of saturated fatty acids.…”

Section: Resultsmentioning

confidence: 99%

Screw press extraction of Sacha inchi seeds: Oil yield and its chemical composition and antioxidant properties

Muangrat

Veeraphong

Chantee

2018

J Food Process Preserv

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In this work, the effects of operating parameters, such as drying temperature (60, 75, 90 °C) and press head temperature (60, 75, 90 °C), on oil yields from Sacha inchi (Plukenetia volubilis L.) seeds were studied using a single screw press machine. It is found that non‐dried Sacha inchi samples gave a high oil yield compared to dried samples for all press head temperatures. These Sacha inchi oils contained high content of polyunsaturated fatty acids, mainly α‐linolenic and linoleic acids. The total content of phenolic compounds in these oils ranges from 30.46 to 120.32 mg GAE/100g oil, DPPH IC50 value 317.33 to 663.54 mg/mL, and ABTS IC50 value 215.48 to 301.75 mg/mL. Additionally, these oil samples have peroxide (1.94–2.27 meq O2/kg oil), iodine (102.66–104.05 g I2/100g oil), saponification (182.18–195.11 mg KOH/g oil) and acid (1.94–5.90 mg KOH/g oil) values, as well as the free fatty acid percentages (0.97–2.97%). Practical applications Screw press extraction is a cost‐efficient method, requiring a shorter extraction time than solvent extraction process and leaving no solvent residues in the oil product. Here, a single screw press machine at different press head temperatures was used to extract oil from Sacha inchi seeds. The various Sacha inchi oil extracts had differences in their fatty acid levels. Additionally, the Sacha inchi oil was found to contain total phenolic compounds, which can be potentially used as an alternative source of natural antioxidants in pharmaceutical or food industries.

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Section: Resultsmentioning

confidence: 99%

Screw press extraction of Sacha inchi seeds: Oil yield and its chemical composition and antioxidant properties

Muangrat

Veeraphong

Chantee

2018

J Food Process Preserv

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“…Several natural oils have been reported as efficient moisturizing agents through their emollient and occlusive properties . For example, olive oil, one of the most commonly used moisturizing products, has been reported to provide moisturizing, anti‐bacterial, anti‐inflammatory, and UV protection activities . These activities are associated with the presence of fatty acids, including omega‐3 (α‐linolenic acid, 0.5%‐0.9%), omega‐6 (linoleic acid, 2%‐10%), and nonessential omega‐9 (oleic acid, up to 78%‐80%) fatty acids, squalene and phenolics .…”

Section: Introductionmentioning

confidence: 99%

“…4,5 For example, olive oil, one of the most commonly used moisturizing products, has been reported to provide moisturizing, anti-bacterial, anti-inflammatory, and UV protection activities. [6][7][8] These activities are associated with the presence of fatty acids, including omega-3 (α-linolenic acid, 0.5%-0.9%), omega-6 (linoleic acid, 2%-10%), and nonessential omega-9 (oleic acid, up to 78%-80%) fatty acids, squalene and phenolics. [6][7][8][9] However, olive oil has been reported to disrupt the skin barrier, thereby acting as an irritant and causing erythema.…”

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confidence: 99%

“…[6][7][8] These activities are associated with the presence of fatty acids, including omega-3 (α-linolenic acid, 0.5%-0.9%), omega-6 (linoleic acid, 2%-10%), and nonessential omega-9 (oleic acid, up to 78%-80%) fatty acids, squalene and phenolics. [6][7][8][9] However, olive oil has been reported to disrupt the skin barrier, thereby acting as an irritant and causing erythema. 10,11 Because a high amount of oleic acid is present in olive oil, such disruption is possibly a result of the interaction between SC lipids and oleic acid.…”

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confidence: 99%

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Evaluation of moisturizing and irritation potential of sacha inchi oil

Soimee

Nakyai

Charoensit

et al. 2019

J of Cosmetic Dermatology

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Objective The moisturizing and irritation effects of sacha inchi oil were evaluated. Study Design The moisturizing effect on the skin was clinically assessed using a regression study design. Sacha inchi oil or olive oil (benchmark) was applied on the left or right lower leg of the subjects for 14 days followed by application discontinuation for 2 days. The TEWL, skin moisture content and dryness appearance were observed. Methods The fatty acid composition and characteristics of cold‐pressed sacha inchi seed oil were determined. Skin tissues cultured ex vivo were used to assess primary irritation induced by the oil by examining keratin 1 expression and TNF‐α and IL‐1α release from the oil‐applied tissues. Results The sacha inchi oil contained 42.3% linolenic acid and 39.5% linoleic acid. This oil's saponification, iodine, acid and peroxide values were 168.58 ± 1.55 mg KOH/g, 203.00 ± 0.04 g I2/100 g, 1.68 ± 0.03 mg KOH/g, and 1.95 ± 0.26 mEq peroxide/kg, respectively. Compared with nontreated skin tissues, induced secretion of TNF‐α and IL‐1α and disruption of keratin 1 integrity in the stratum corneum layer were not found in the sacha inchi oil‐treated tissues. In a clinical study with 13 volunteers, the improvement in moisture content and skin dryness appearance at the sacha inchi oil‐applied site was comparable with that observed at the olive oil‐applied site. Conclusions The sacha inchi oil was mild to the skin and benefited dry skin.

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“…El aceite de Plukenetia volubilis contiene ácidos grasos poliinsaturados (78,15-84,49%), monoinsaturados (7,50-10,71%) y saturados (6,74-7,70%); siendo el omega 3 (45,2-50,41%) y el omega 6 (32,66-36,8%), los principales poliinsaturados y el omega 9 (8,41-10,45%), el principal monoinsaturado; también contiene tocoferoles y esteroles (2) . Se ha reportado como actividades biológicas del aceite: que afecta la adherencia del Staphylococcus aureus a los queratinocitos y elimina a esta bacteria de los queratinocitos y explantes de piel humana (3) , reduce la masa tumoral y proliferación de células del tumor de Walker 256 ex vivo, reduce los niveles plasmáticos de citoquinas inflamatorias (TNF-alfa e interleuquina IL-6) de ratas portadoras del tumor de Walker 256 (4) , actividad antidislipidémica en ratas (5) y en humanos (6)(7)(8) . Se ha reportado escasos estudios preclínicos de toxicidad sobre este aceite (3,5) .…”

Section: Introductionunclassified

Composición química, características físico-químicas, trazas metálicas y evaluación genotóxica del aceite de Plukenetia volubilis L. (sacha inchi)

Aranda-Ventura¹,

Villacrés-Vallejo²,

Rios-Isern³

2019

Rev. per. med. integr.

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Objetivos. Determinar la composición química, características físico-químicas y el efecto genotóxico del aceite de Plukenetia volubilis L. Materiales y métodos. Se evaluó el perfil de ácidos grasos, tocoferoles, esteroles,fosfolípidos,carotenoides,tocotrienoles y fenoles; así como las características físico-químicas y trazas metálicas. La genotoxicidad fue evaluada a través del ensayo de morfología de la cabeza de espermatozoides. Para este ensayo, se emplearon ratones albinos machos formando 3 grupos de experimentación de 7 animales cada uno: control negativo (solución salina 0,9%), control positivo (50 mg/kg/pc/día de ciclofosfamida) y grupo problema que recibió por vía oral 0,5 ml de aceite sacha inchi (NIMET); las sustancias se administraron cada 24 horas por 5 días. Resultados. El aceite contiene ácidos grasos poliinsaturados(81,72%),monoinsaturados(10,31%) y saturados(7,67%); siendo el alfa-linolénico (47,35%) y el linoleico (34,34%) los más abundantes. El tocoferol y esterol más abundante fueron el gamma-tocoferol y el beta-siitosterol respectivamente,y en escasa cantidad se halló: fenoles,fosfolípidos,carotenoides y tocotrienoles. Los índices de refracción, saponificación, yodo, peróxido y de acidez, fueron 1,48, 189 mg KOH/g, 190, 0,9 meq/kg, 1,11 KOH/g respectivamente. La densidad, materia insaponificable y humedad y materias volátiles fueron 0,9276, 0,27%, 0,05% respectivamente. Los niveles de arsénico y de plomo, no excedieron los límites máximos permisibles. El grupo de ciclofosfamida mostró una cantidad mayor de espermatozoides anormales (P<0,01) con respecto a los grupos de solución salina y NIMET; no se halló diferencia significativa entre los grupos de solución salina y NIMET. Conclusiones. El aceite de Plukenetia volubilis, es rico en ácidos grasos esenciales alfa-linolénico y linoleico, con una óptima proporción omega 6/omega 3, con significativas cantidades de tocoferoles y fitoesteroles los cuales le brindan una estabilidad oxidativa y con características físico-químicas que corroboran su calidad. En este diseño evaluado el aceite de sacha inchi no induce genotóxicidad, podemos decir que su consumo es seguro como alimento. Palabras clave: Plukenetia volubilis, ácidos grasos, tocoferoles, esteroles, genotoxicidad, morfología espermatozoides (Fuente: DeCS)

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Sacha Inchi Oil (Plukenetia volubilis L.), effect on adherence of Staphylococus aureus to human skin explant and keratinocytes in vitro

Cited by 46 publications

References 20 publications

Screw press extraction of Sacha inchi seeds: Oil yield and its chemical composition and antioxidant properties

Screw press extraction of Sacha inchi seeds: Oil yield and its chemical composition and antioxidant properties

Evaluation of moisturizing and irritation potential of sacha inchi oil

Composición química, características físico-químicas, trazas metálicas y evaluación genotóxica del aceite de Plukenetia volubilis L. (sacha inchi)

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