Sacroiliitis secondary to catheter-related bacteremia due to Mycobacterium abscessus (sensu stricto)

Abstract

We describe a case of sacroiliitis secondary to catheter-related bacteremia due to Mycobacterium abscessus (sensu stricto). This case confirms that MultiLocus sequence typing and variable-number tandem-repeat methods are very robust techniques to identify the pathogen species and to validate molecular epidemiological links among complex M. abscessus isolates.

Septic sacroiliitis in the late postpartum due to Escherichia coli

“…Through the search strategy, 359 articles were identified, 341 from the Pubmed database and 18 from the BVS; of them, after applying the inclusion and exclusion criteria, 17 articles were obtained, of which 32 cases were extracted. [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34] (Table 1) In addition to all cases reported to date, those in which the infection was associated with pregnancy were extracted and analyzed (Table 2). 4,9,13,21,25,[32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48] All articles included were classified according to the "Oxford Center for Evidence-based Medicine" at levels 4 or 5.…”

Catheter-related infections caused by Mycobacterium abscessus in a patient with motor neurone disease: A case report

“…Gram positive cocci (such as staphylococcus epidermidis, staphylococcus aureus, and enterococcus) have been historically the leading cause of CRBSI[ 15 ]. Catheter-related M. abscessus infection is relatively rare, with limited literature reports[ 7 , 8 ]. In the present study, M. abscessus was identified by matrix-assisted laser desorption ionization-time of flight mass spectrometry and 16S rDNA sequencing.…”

“…The main threat of M. abscessus is its antibiotic resistance. M. abscessus may be the most resistant species among pathogenic rapidly growing mycobacteria, and its antimicrobial therapy is still a challenge[ 8 ]. A previous study showed that the treatment strategy of M. abscessus infections was the combination of multiple antibiotics, including amikacin, ofloxacin, ciprofloxacin, clarithromycin, and doxycycline[ 16 ].…”

“…In the present study, the patient received anti-infective treatment with amikacin plus clarithromycin. In addition, in the case of catheter-related M. abscessus infections, removal of the catheter is necessary due to the high incidence of relapsing or uncontrolled bacteremia[ 8 ]. After the removal of the PICC of our patient, he continued to receive anti-infective treatment with amikacin plus clarithromycin, and his body temperature was maintained at a basic level (35-36.3 ° C).…”

“…However, M. abscessus is resistant to most antibiotics in vitro, and thus is a formidable and difficult-to-treat pathogen[ 6 ]. At present, little is known regarding the diagnosis and management of catheter-related M. abscessus infections due to only a limited number of cases that have been reported[ 7 , 8 ]. Here, we present a case of catheter-related M. abscessus infections in a patient with motor neurone disease.…”