“…Twenty-three articles were considered eligible for answering the research question after selection based on title and abstract. Seventeen articles were excluded during full text screening because of the following reasons: incorrect domain (n = 1) [9], outcome not focusing on safety, efficacy, and complications (n = 1) [10], CVC use in pediatrics (n = 7) [11], [12], [13], [14], [15], [16], [17], in vitro studies (n = 4) [18], [19], [20], [21], no original article (n = 3) [1], [22], [23], and not meeting language requirements (n = 1) [24]. During cross referencing, one study was included missed by the initial search [25].…”