Safe handling of cytotoxics: guideline recommendations

Abstract

The recommendations differ slightly from earlier guidelines because of the availability of new evidence.

Semiautomated aseptic preparation of patient-individual antineoplastic intravenous solutions: first experiences in a German hospital pharmacy

“…The first experiences in automated antineoplastic drug preparation have been published in 19902 and various experiences with fully automated robots followed more than one decade later,3 4 but approaches and local conditions that influence use and output of the device are different. In addition, there is already evidence that robotic devices are able to produce very low contamination levels,5 and therefore, might be capable of enhancing staff safety 6…”

Regulatory verification on safe use of cytotoxic drugs in veterinary clinics and animal hospitals

“…There are no published studies on surface monitoring of CTD contamination in the veterinary care sector in Australia. Only three overseas publications were noted . We met our objective to identify areas of contamination so that control measures can be targeted to help minimise workers’ exposure to CTDs.…”

“…Only three overseas publications were noted. [14][15][16][17] We met our objective to identify areas of contamination so that control measures can be targeted to help minimise workers' exposure to CTDs.…”

“…The contaminated locations were mainly CTD infusion treatment areas and patients' toilets. Control measures that include closed drug‐transfer systems and stringent use of personal protective equipment (PPE) appear to minimise workers’ exposure to CTDs …”

An ethical imperative: Safety and specialization as nursing priorities of WHO Global Initiative for Childhood Cancer

“…There has been a persistent failure in LMIC to ensure access to PPE for safe preparation, administration, and disposal of chemotherapy for nurses, pharmacists, and physicians . This includes chemotherapy‐tested gloves, masks, protective eyewear and disposable impermeable gowns, and at minimum, a level 2B biosafety cabinet with appropriate ventilation . There is also a lack of appropriate training for health professionals in safe handling practices, although there are increasing efforts to address this …”