Safety and effectiveness of medication and aspiration abortion before or during the sixth week of pregnancy: A retrospective multicenter study

Baldwin, Maureen K.; Bednarek, Paula H.; Russo, Jennefer A.

doi:10.1016/j.contraception.2020.04.004

Cited by 9 publications

(9 citation statements)

References 14 publications

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“…Research conducted in the United States during the 1970s indicated that surgical abortion procedures performed at ≤6 weeks' gestation, compared with 7-12 weeks' gestation, were less likely to result in successful termination of the pregnancy (74). However, subsequent advances in technology (e.g., improved transvaginal ultrasonography and sensitivity of pregnancy tests) have allowed very early surgical abortions to be performed with completion rates exceeding 97% (75)(76)(77)(78). Likewise, the development of early medical abortion regimens has allowed for abortions to be performed early in gestation, with completion rates for regimens that combine mifepristone and misoprostol reaching 96%-98% (78-81).…”

Section: Discussionmentioning

confidence: 99%

“…However, subsequent advances in technology (e.g., improved transvaginal ultrasonography and sensitivity of pregnancy tests) have allowed very early surgical abortions to be performed with completion rates exceeding 97% ( 75 – 78 ). Likewise, the development of early medical abortion regimens has allowed for abortions to be performed early in gestation, with completion rates for regimens that combine mifepristone and misoprostol reaching 96%–98% ( 78 – 81 ). Among those that were eligible (≤9 weeks’ gestation), 53.7% were reported as early medical abortions.…”

Section: Discussionmentioning

confidence: 99%

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Abortion Surveillance — United States, 2019

Kortsmit

Mandel

Reeves

et al. 2021

MMWR Surveill. Summ.

111

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Problem/Condition CDC conducts abortion surveillance to document the number and characteristics of women obtaining legal induced abortions and number of abortion-related deaths in the United States. Period Covered 2019. Description of System Each year, CDC requests abortion data from the central health agencies for 50 states, the District of Columbia, and New York City. For 2019, 49 reporting areas voluntarily provided aggregate abortion data to CDC. Of these, 48 reporting areas provided data each year during 2010–2019. Census and natality data were used to calculate abortion rates (number of abortions per 1,000 women aged 15–44 years) and ratios (number of abortions per 1,000 live births), respectively. Abortion-related deaths from 2018 were assessed as part of CDC’s Pregnancy Mortality Surveillance System (PMSS). Results A total of 629,898 abortions for 2019 were reported to CDC from 49 reporting areas. Among 48 reporting areas with data each year during 2010–2019, in 2019, a total of 625,346 abortions were reported, the abortion rate was 11.4 abortions per 1,000 women aged 15–44 years, and the abortion ratio was 195 abortions per 1,000 live births. From 2018 to 2019, the total number of abortions increased 2% (from 614,820 total abortions), the abortion rate increased 0.9% (from 11.3 abortions per 1,000 women aged 15–44 years), and the abortion ratio increased 3% (from 189 abortions per 1,000 live births). From 2010 to 2019, the total number of reported abortions, abortion rate, and abortion ratio decreased 18% (from 762,755), 21% (from 14.4 abortions per 1,000 women aged 15–44 years), and 13% (from 225 abortions per 1,000 live births), respectively. In 2019, women in their 20s accounted for more than half of abortions (56.9%). Women aged 20–24 and 25–29 years accounted for the highest percentages of abortions (27.6% and 29.3%, respectively) and had the highest abortion rates (19.0 and 18.6 abortions per 1,000 women aged 20–24 and 25–29 years, respectively). By contrast, adolescents aged <15 years and women aged ≥40 years accounted for the lowest percentages of abortions (0.2% and 3.7%, respectively) and had the lowest abortion rates (0.4 and 2.7 abortions per 1,000 women aged <15 and ≥40 years, respectively). However, abortion ratios in 2019 were highest among adolescents (aged ≤19 years) and lowest among women aged 25–39 years. Abortion rates decreased from 2010 to 2019 for all women, regardless of age. The decrease in abortion rate was highest among adolescents compared with any other age group. From 2018 to 2019, abortion rates decreased or did not change among women aged ≤24 years; however, the abortion rate increased among those aged ≥25 years. Abortion ratios also decreased or did not change from 2010 to 2019 for all age groups, except adolescents aged <15 years. The decrease in abortion ratio was highest among women aged ≥40 years compared with any other age group. From 2018 to 2019, ab...

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Abortion Surveillance — United States, 2019

Kortsmit

Mandel

Reeves

et al. 2021

MMWR Surveill. Summ.

111

View full text Add to dashboard Cite

show abstract

“…Research conducted in the United States during the 1970s indicated that surgical abortion procedures performed at ≤6 weeks' gestation, compared with 7-12 weeks' gestation, were less likely to result in successful termination of the pregnancy (70). However, subsequent advances in technology (e.g., improved transvaginal ultrasonography and sensitivity of pregnancy tests) have allowed very early surgical abortions to be performed with completion rates exceeding 97% (71)(72)(73)(74). Likewise, the development of early medical abortion regimens has allowed for abortions to be performed early in gestation, with completion rates for regimens that combine mifepristone and misoprostol reaching 96%-98% (74)(75)(76)(77).…”

Section: Discussionmentioning

confidence: 99%

“…However, subsequent advances in technology (e.g., improved transvaginal ultrasonography and sensitivity of pregnancy tests) have allowed very early surgical abortions to be performed with completion rates exceeding 97% (71)(72)(73)(74). Likewise, the development of early medical abortion regimens has allowed for abortions to be performed early in gestation, with completion rates for regimens that combine mifepristone and misoprostol reaching 96%-98% (74)(75)(76)(77). In 2018, 77.7% of all reported abortions were ≤9 weeks' gestation thus were eligible for early medical abortion; of these, 50.0% were reported as medical abortions.…”

Section: Discussionmentioning

confidence: 99%

Abortion Surveillance — United States, 2018

Kortsmit¹,

Jatlaoui²,

Mandel³

et al. 2020

MMWR Surveill. Summ.

View full text Add to dashboard Cite

Problem/Condition: CDC conducts abortion surveillance to document the number and characteristics of women obtaining legal induced abortions and number of abortion-related deaths in the United States. Period Covered: 2018. Description of System: Each year, CDC requests abortion data from the central health agencies for 50 states, the District of Columbia, and New York City. For 2018, 49 reporting areas voluntarily provided aggregate abortion data to CDC. Of these, 48 reporting areas provided data each year during 2009-2018. Census and natality data were used to calculate abortion rates (number of abortions per 1,000 women aged 15-44 years) and ratios (number of abortions per 1,000 live births), respectively.

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“…Whereas Mansoor et al, conducted a comparative study between MVA and Dilatation and curettage under general anaesthesia and found the efficacy to be 96% and 100% respectively 4 . Russo et al, conducted a multicentric retrospective chart review study at Columbia to compare medical termination with aspiration technique in pregnancy of <49 days in 2014-15 and documented lesser adverse effects in the aspiration group 5.8 vs 2.7% respectively 13 . Alisa et al, recorded no difference in rates of uterine reaspiration while comparing outcomes of manual (2.2%) with electronic (1.7%) vacuum aspiration in USA.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Efficacy of Electronic Vacuum Aspiration With Intravenous Analgesia

Afsheen

Shahid

Iftikhar

et al. 2021

PAFMJ

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Objective: To assess efficacy of elecrtonic vacuum aspiration in evacuation of retained product of conception with intravenous analgesia. Study Design: A prospective observational study. Place and Duration of Study: Department of Gynaecology and Obstetrics, Pakistan Naval Ship Shifa Hospital, Karachi Pakistan, from Jan to Jun 2018. Methodology: All patients who were intended to undergo Electronic Vacuum Aspiration due to retained products of conception, early fetal demise, septic induced abortions and molar (all upto 12 weeks of gestation) were enrolled in this study after obtaining informed consent. Outcome measures of study were efficacy (defined as completeness of the evacuation procedure confirmed by ultrasound), occurrence of complications like uterine perforation, excessive bleeding >200ml and sepsis (diagnosed clinically or biochemically). Results: A total of 1080 patients underwent Electronic Vacuum Aspiration during the study period. Complete evacuation was achieved in 1026 (95%) cases. Four (<1%) patients experienced post procedure infection while none had uterine perforation. Average blood loss was <100ml while 18 (1.6%) patients had blood loss of >200ml. Conclusion: Electronic vacuum aspiration is a safe and efficacious method of uterine evacuation. It does not require special equipment. It is easy to learn and is readily available as well as cost effective. Hence it’s a very lucrative alternative to manual vacuum aspiration using I pass or medical termination of pregnancy in resource poor settings.

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Safety and effectiveness of medication and aspiration abortion before or during the sixth week of pregnancy: A retrospective multicenter study

Cited by 9 publications

References 14 publications

Abortion Surveillance — United States, 2019

Abortion Surveillance — United States, 2019

Abortion Surveillance — United States, 2018

Assessment of Efficacy of Electronic Vacuum Aspiration With Intravenous Analgesia

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