The 2009 H1N1 influenza pandemic created a demand for health-care services that many health-care systems and providers were unprepared to meet in a timely way. One state used a public-private partnership to address this increased demand for information and services, including offering a prescription for those whose symptoms warranted treatment with an antiviral medication. Spaulding et al. describe how the Minnesota Department of Health worked with a variety of partners, including the Minnesota Hospital Association and the Minnesota Council of Health Plans, to establish a coordinated statewide nurse triage line-the Minnesota FluLine. This effort could serve as a model for other local public health departments when a rapid response to a health-care threat is needed.