Safety and efficacy of coronary sinus narrowing in chronic refractory angina: Insights from the RESOURCE study

Ponticelli, Francesco; Khokhar, Arif; Leenders, Geert E.; Konigstein, Maayan; Zivelonghi, Carlo; Agostoni, Pierfrancesco; Kuijk, Jan-Peter van; Ajmi, Issameddine; Lindsay, Steven; Bunc, Matjaž; Tebaldi, Matteo; Cafaro, Alessandro; Cheng, Kevin; Ielasi, Alfonso; Patterson, Tiffany; Wolter, Jan Sebastian; Sgura, Fabio; Marco, Federico De; Ioanes, Dan; D’Amico, Gianpiero; Ciardetti, Marco; Berti, Sérgio; Guarracini, Stefano; Mauro, Michele Di; Gallone, Guglielmo; Dekker, Mirthe; Silvis, Max J. M.; Tarantini, Giuseppe; Redwood, Simon; Colombo, Antonio; Liebetrau, Christoph; Silva, Ranil de; Rapezzi, Claudio; Ferrari, Roberto; Campo, Gianluca; Schnupp, Steffen; Timmers, Leo; Verheye, Stefan; Stella, Pieter R.; Banai, Shmuel; Giannini, Francesco

doi:10.1016/j.ijcard.2021.05.034

Cited by 20 publications

(7 citation statements)

References 22 publications

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“…The coronary sinus reducer, initially proposed and applied to surgical procedures in the 1940s and 1950s (43,44), then abandoned in the 1960s with the rise of bypass surgery, regained attention as a potential treatment option. Clinical trials confirmed its feasibility and safety (45)(46)(47), but additional research is needed to comprehend its mechanism of action, long-term benefits and individual adaptability (48).…”

Section: Discussionmentioning

confidence: 99%

Refractory angina pectoris: a 20-year (2003–2022) bibliometric analysis

Chen,

Ge,

Chao

et al. 2023

Front. Cardiovasc. Med.

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BackgroundThe increasing number of patients with refractory angina pectoris, combined with the aging population and improved survival rates among coronary heart disease patients, presents a significant challenge in contemporary cardiovascular medicine. The treatment of refractory angina has been an ongoing area of exploration, yet a comprehensive analysis of the existing literature on this topic is currently lacking. Therefore, this study aims to provide the first bibliometric analysis of publications related to refractory angina.MethodsA systematic search was conducted in the Web of Science database to identify articles related to refractory angina published between 2003 and 2022. The inclusion criteria were limited to articles and reviews written in English. CiteSpace software was utilized to conduct a collaborative network analysis of countries/regions, institutions and authors, co-occurrence analysis of keywords, and co-citation analysis of authors and references.ResultsA total of 1,386 publications were identified, with an annual publication volume exhibiting fluctuation over time. American and European countries and institutions demonstrated a leading position in terms of research output. Henry TD emerged as the most prolific researcher in the field, while Mannheimer C received the highest number of citations. The primary research hotspot within this field focused on the treatment of refractory angina, with recent emphasis on emerging treatments such as stem cell therapy and the coronary sinus reducer. A significant number of clinical trials have been conducted, with a continuous focus on patient benefits, quality of life, and survival prognosis.ConclusionSignificant progress has been made in the field of refractory angina pectoris in recent years. Novel treatment methods, including spinal cord stimulation, enhanced external counterpulsation, stem cell therapy, and the coronary sinus reducer, hold promising therapeutic prospects. However, further high-quality evidence-based research is essential to support these emerging interventions. Additionally, the development of comprehensive evidence-based guidelines for refractory angina treatment is crucial. Such guidelines would provide clinicians with a framework to navigate the complexities of treatment choices and optimize patient care in this challenging condition.

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Section: Discussionmentioning

confidence: 99%

Refractory angina pectoris: a 20-year (2003–2022) bibliometric analysis

Chen,

Ge,

Chao

et al. 2023

Front. Cardiovasc. Med.

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“…Ponticelli et al 55 have tried to measure the safety and efficacy of the CSRS implantation chronic RAP patients retrospective registry that includes 658 patients with RAP from 20 centers in Europe, United Kingdom, and Israel was conducted. At a median follow-up of 502 days (IQR 225–1091) after CSRS implantation, 39.7% of patients improved by a least two CCS classes and 76% by at least one class.…”

Section: Medical Therapiesmentioning

confidence: 99%

Nonpharmacological interventions for ‘no-option’ refractory angina patients

Paz,

Levy,

Grosman-Rimon

et al. 2023

Journal of Cardiovascular Medicine

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Refractory angina pectoris (RAP) defined as chronic anginal chest pain because of coronary artery disease (CAD) is a major problem. The increase in the number of patients with RAP in recent years is because of the increasing aging population and improved survival rates among patients with CAD. Management of patients with RAP is often extremely challenging. In this review, we present several interventional approaches for RAP, including device therapies, lifestyle intervention, and cell therapies. Some of these treatments are currently used in the management of RAP, whereas other treatments are under investigation.

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“…In this context, the coronary sinus (CS) Reducer is a novel technology designed to improve quality of life and functional capacity by reducing angina burden. The clinical utilization of this device-based therapy for refractory angina continues to grow, with encouraging clinical evidence to support its safety and efficacy [4][5][6][7]. The Reducer is the only therapy that attempts to improve angina by acting on the postcapillary myocardial circulation.…”

Section: Related Article By Mrak Et Almentioning

confidence: 99%

Safety and efficacy of coronary sinus narrowing in chronic refractory angina: Insights from the RESOURCE study

Cited by 20 publications

References 22 publications

Refractory angina pectoris: a 20-year (2003–2022) bibliometric analysis

Refractory angina pectoris: a 20-year (2003–2022) bibliometric analysis

Nonpharmacological interventions for ‘no-option’ refractory angina patients

Coronary sinus Reducer: An adjunctive tool for the treatment of patients with chronic total occlusion of the right coronary artery

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