Safety and efficacy of Implanon™, a single-rod implantable contraceptive containing etonogestrel

Funk, Sidney; Miller, Michael M.; Mishell, Daniel R.; Archer, David F.; Poindexter, Alfred N.; Schmidt, J.; Zampaglione, Edio

doi:10.1016/j.contraception.2004.11.007

Cited by 200 publications

(138 citation statements)

References 16 publications

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“…The Pearl index found in this study was 0% as there was no pregnancy among users over the five year period. This is in agreement with reports of Affandi et al, (1999), Funk et al, (2005) and Power et al, (2007).…”

Section: Discussionsupporting

confidence: 83%

“…The two commonest reasons for discontinuation of Implanon were the desire to get pregnant (35%) and menstrual disturbance (26.1%) respectively. However, most other studies reported menstrual abnormalities as the leading cause of discontinuation (Funk et al, 2005, Sergent et al, 2004, Lakha et al, 2006. Aisien et al, (2010) reported from Benin City that most of the subjects found menstrual abnormalities tolerable with adequate counseling.…”

Section: Discussionmentioning

confidence: 99%

“…Marketing of Implanon was started in 1998 (Association of reproductive health professionals, 2008); it is a single 4 cm long 2 mm wide (Okpere, 2007;Burkman, 2007) rod with an ethylene vinyl acetate (EVA) copolymer core containing 68 mg etonogestrel (Okpere, 2007). The rate of release in the early weeks of insertion is 60-70 µg per day (Affandi et al, 1999), it decreases to about 25-30 µg per day by the end of third year (Organon, 2006) but 25-30 µg per day of etonogestrel is needed to suppress ovulation (Funk et al, 2005). The onset of contraception is within 24 hrs of insertion, the cumulative failure rate is low (Ladipo et al, 2005) and the Pearl index is 0 (Affandi et al, 1999, Funk et al, 2005.…”

Section: Introductionmentioning

confidence: 99%

“…Its side effects include menstrual abnormalities, emotional lability, weight increase, depression and acne but with a rapid return of fertility when it is removed (Funk et al, 2005, Sergent et al, 2004. It is relatively new compared to other earlier methods in this centre and thus, it is important to evaluate its performance profile.…”

Section: Introductionmentioning

confidence: 99%

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Implanon sub-dermal implant: an emerging method of contraception in Ilorin, Nigeria

Balogun¹,

Olaomo²,

Adeniran³

et al. 2014

J. Med. Biomed. Sci.

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Implanon, a single rod sub-dermal implant is a relatively new contraceptive which offers long term reversible contraception for women. This study seeks to determine the safety, efficacy and acceptor characteristics of Implanon at the family planning clinic of University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria. This study involves a retrospective review of 88 clients who used Implanon from January 2007 to December 2011 at the family planning clinic of the UITH, Ilorin. Of the 2,456 clients who had contraception during the period, 88 had Implanon giving a 3.6% uptake. The mean age of Implanon users in the study was 33.4 years, no teenager used the method and 72 (81.8%) knew about the method from clinic staff. Women with two living children constituted 29 (33%) of the total users, 78(88.6%) users had at least secondary education, all except one client were married and religion did not influence its use. Twenty two (25%) users had side effects, the commonest being menstrual irregularity in 13(59%) of the participants. Discontinuation rate was 26.1% and the commonest reason for discontinuation was the desire to get pregnant 8(35%). The Pearl Index for Implanon in the study was 0. Implanon is an effective long term hormonal contraceptive appropriate in a wide range of women with tolerable side effect profile but is currently underutilised. Wider publicity, education and access are needed to improve client uptake..

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Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Implanon sub-dermal implant: an emerging method of contraception in Ilorin, Nigeria

Balogun¹,

Olaomo²,

Adeniran³

et al. 2014

J. Med. Biomed. Sci.

View full text Add to dashboard Cite

show abstract

“…On the other hand, even though the medical literature is limited, 12-month continuation and satisfaction rates for LARCs remains high -68 -82% [35][36] . While the objective of our study did not directly address continuation and satisfaction rates, we noted that none of the new LARCs acceptors discontinued during the eleven-month study period.…”

Section: Discussionmentioning

confidence: 99%