Safety and efficacy of intracameral moxifloxacin for prevention of post-cataract endophthalmitis: Randomized controlled clinical trial

The Anterior Chamber Injection of Moxifloxacin Injection to Prevent Endophthalmitis after Cataract Surgery: A Meta-analysis

“…A total of 2,686 articles were collected through relevant database searches and other resources, and 262 duplicates were deleted. After exclusion according to the topic, abstract, and intensive reading of the full text, 8 articles were finally included [11][12][13][14][15][16][17][18]. e literature was analyzed by Meta.…”

“…is meta-analysis included 8 studies [11][12][13][14][15][16][17][18], with 123,819 eyes; 2 studies were RCTs [11,17], 2 studies were case-control studies [12,13], and 4 studies were cohort studies [14][15][16]18]. Two studies [11,14] were conducted in Brazil, 1 study [17] was conducted in the USA, 1 study [12]was conducted in Turkey, 1 study [13] was conducted in Canada, 1 study [18] was conducted in Colombia, and 2 studies [15,16] were conducted in Japan. e follow-up time ranged from 2 weeks to 1 year.…”

“…e basic characteristics of the literature are shown in Table 1. [11,17] were RCTs, and we used the Cochrane risk of bias tool to assess these studies; the RCTquality evaluation results are shown in Figures 2 and 3. For non-RCTs [12][13][14][15][16]18], we used the Newcastle-Ottawa scoring system to evaluate the quality of the literature.…”

“…e meta-analysis showed no significant difference between the moxifloxacin injection and nonmoxafloxacin injection (OR � 1.03, 95% CI (0.23, 4.69), P � 0.97, Figure 8). ree studies [11,15,17] reported CCT, and there was no heterogeneity between the studies (I 2 � 0%, P � 0.58); therefore, a fixed effect model was used. e metaanalysis showed no significant difference between the moxifloxacin injection and nonmoxifloxacin injection (SMD � −0.01, 95% CI (−0.07, 0.05), P � 0.77, Figure 9).…”

Comparing Resident Outcomes in Cataract Surgery at Different Levels of Experience: A retrospective case series

“…Intracameral moxi oxacin (Vigamox®) was injected as the nal step of the surgery (150 µg in 0.03 ml). (20) In the immediate postoperative period, patients received 0.5% moxi oxacin and 0.1% dexamethasone eye drops prior to bandaging. Similarly, the topical postoperative regimen consisted of 0.5% moxi oxacin combined with 0.1% dexamethasone every 3 hours for 7 days only during waking hours.…”