Aiming at the problem that Automated guided vehicle (AGV) faces dynamic and static obstacles in the process of transporting patients in medical environment and needs to avoid in real time, inspired by the behavior of antelopes during migration, this paper proposes a bionic obstacle avoidance strategy based on adaptive behavior of antelopes. The traditional artificial potential field and dynamic window algorithm are improved by using the bionic characteristics of antelope migration.By adding new potential field force points and improving the window size, the success rate and prediction range of AGV navigation are improved.Simulation experiments were carried out through the numerical simulation platform, and the verification results showed that:The bionic obstacle avoidance strategy proposed in this paper can avoid dynamic and static obstacles at the same time. In the example, the success rate of path planning is increased by 34%, the running time is reduced by 33%, and the average path length is reduced by 1%. The proposed method can realize the integration of “dynamic and static” avoidance in the process of transporting patients, and effectively save the time of transporting patients by AGV.It provides a theoretical basis for realizing obstacle avoidance and rapid loading of AGV in medical environment.