Safety and Efficacy of Radiofrequency Ablation for Hepatocellular Adenoma

Vledder, Mark G. van; Aalten, Sanne M. van; Terkivatan, Türkan; Man, Robert A. de; Leertouwer, Trude C.; IJzermans, Jan N.M.

doi:10.1016/j.jvir.2011.02.024

Cited by 54 publications

(38 citation statements)

References 22 publications

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“…Apart from the classic surgical resection, which remains the gold standard procedure, 21 several studies have supported the development of alternative treatments such as laparoscopic resection in an expert center 139,140 and radiofrequency 141 to reduce postoperative complications. Liver transplantation should be avoided except for patients with glycogenosis 1a-associated adenomatosis because liver transplantation treats both the HCA and the underlying metabolic disorder.…”

Section: Translation In Clinical Carementioning

confidence: 99%

Hepatocellular Benign Tumors—From Molecular Classification to Personalized Clinical Care

2013

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Section: Translation In Clinical Carementioning

confidence: 99%

Hepatocellular Benign Tumors—From Molecular Classification to Personalized Clinical Care

2013

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“…in adult patients, we propose a conservative treatment for multiple HCA or adenomatosis, involving resection of the largest tumors and close followup of the remaining small lesions with iterative resection if necessary. The place of percutaneous ablation using either radiofrequency, cryotherapy, or other techniques is still unclear [76]. …”

Section: Hepatocellular Adenomamentioning

confidence: 99%

Benign Hepatocellular Tumors in Children: Focal Nodular Hyperplasia and Hepatocellular Adenoma

Franchi‐Abella

Branchereau

2013

International Journal of Hepatology

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Benign liver tumors are very rare in children. Most focal nodular hyperplasia (FNH) remain sporadic, but predisposing factors exist, as follows: long-term cancer survivor (with an increasing incidence), portal deprivation in congenital or surgical portosystemic shunt. The aspect is atypical on imaging in two-thirds of cases. Biopsy of the tumor and the nontumoral liver is then required. Surgical resection will be discussed in the case of large tumors with or without symptoms. In the case of associated vascular disorder with portal deprivation, restoration of the portal flow will be discussed in the hope of seeing the involution of FNH. HepatoCellular Adenoma (HCA) is frequently associated with predisposing factors such as GSD type I and III, Fanconi anemia especially if androgen therapy is administered, CPSS, and SPSS. Adenomatosis has been reported in germline mutation of HNF1-α. Management will depend on the presence of a predisposing factor and may include metabolic control, androgen therapy withdrawn, or closure of the shunt when appropriate. Surgery is usually performed on large lesions. In the case of adenomatosis or multiple lesions, surgery will be adapted. Close followup is required in all cases.

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“…Orthotopic liver transplantation in adenomatosis remains an exception [18,19]. Interventional radiologists play a role in the management through radiofrequency and embolization of the nodule [20][21][22], two techniques more recently proposed in this indication.…”

Section: The Surgical Management Of Hcamentioning

confidence: 99%

Hepatocellular adenoma management: Call for shared guidelines and multidisciplinary approach

Blanc

Frulio

Chiche

et al. 2015

Clinics and Research in Hepatology and Gastroenterology

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Safety and Efficacy of Radiofrequency Ablation for Hepatocellular Adenoma

Cited by 54 publications

References 22 publications

Hepatocellular Benign Tumors—From Molecular Classification to Personalized Clinical Care

Hepatocellular Benign Tumors—From Molecular Classification to Personalized Clinical Care

Benign Hepatocellular Tumors in Children: Focal Nodular Hyperplasia and Hepatocellular Adenoma

Hepatocellular adenoma management: Call for shared guidelines and multidisciplinary approach

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