Safety and efficacy of scalp hypothermia to prevent chemotherapy-induced alopecia: A study of a scalp-cooling system used in breast cancer women in a Mexican public hospital.

Campos-Gomez, Saúl; Cruz, Lucia Rojas; N, Morales; Gomez, Karen Angelica Campos; Mendoza, Blanca Olivares; Garces, Marciela Garcia; Mendez, Yunuen; Ramos, Marlid Cruz; Franco, José Luis; Cabrera, Paula

doi:10.1200/jco.2015.33.15_suppl.e12021

Cited by 1 publication

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“…However, there was no mention of the follow-up time in this patient cohort. Scalp cooling was employed Campos-Gomez [ 23 ] Sixty-eight patients in scalp cooling were reported as followed up on, but it was unclear as to the timeframe of follow-up. No mention as well of scalp metastasis Christodoulou [ 22 ] Two out of 227 breast cancer patients developed scalp metastasis.…”

Section: Resultsmentioning

confidence: 99%

Scalp cooling with adjuvant/neoadjuvant chemotherapy for breast cancer and the risk of scalp metastases: systematic review and meta-analysis

Rugo

Melin

Voigt³

2017

Breast Cancer Res Treat

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PurposeThe risk of scalp metastases in patients using scalp cooling for preservation of hair during chemotherapy has been a concern but is poorly described.MethodsA systematic review and meta-analysis of longitudinal studies was undertaken to evaluate the effect of scalp cooling versus no scalp cooling on the risk of scalp metastasis in patients treated for breast cancer with chemotherapy. Electronic databases, journal specific, and hand searches of articles identified were searched. Patients were matched based on disease, treatment, lack of metastatic disease, and sex.ResultsA total of 24 full-text articles were identified for review. Of these articles, ten quantified the incidence of scalp metastasis with scalp cooling over time. For scalp cooling, 1959 patients were evaluated over an estimated mean time frame of 43.1 months. For no scalp cooling, 1238 patients were evaluated over an estimated mean time frame of 87.4 months. The incidence rate of scalp metastasis in the scalp cooling group versus the no scalp cooling group was 0.61% (95% CI 0.32–1.1%) versus 0.41% (95% CI 0.13–0.94%); P = 0.43.ConclusionThe incidence of scalp metastases was low regardless of scalp cooling. This analysis suggests that scalp cooling does not increase the incidence of scalp metastases.Electronic supplementary materialThe online version of this article (doi:10.1007/s10549-017-4185-9) contains supplementary material, which is available to authorized users.

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