Safety and health in boatbuilding and repair

Brigham, Christopher R.; Landrigan, Philip J.

doi:10.1002/ajim.4700080303

Cited by 22 publications

(7 citation statements)

References 14 publications

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“…Hunting (20) reported that, in a prospective study of union painters using oil-based paints, exposure to solvents was associated with slips and falls. Boat builders are another occupational group exposed to sol vents, and they are known to be at increased risk of fall injury (21). The role of solvent exposure in severe occupational falls is an area needing further study.…”

Section: Discussionmentioning

confidence: 99%

Work-related deaths in construction painting.

Aj¹

1992

Scand J Work Environ Health

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Section: Discussionmentioning

confidence: 99%

Work-related deaths in construction painting.

Aj¹

1992

Scand J Work Environ Health

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“…Styrene is associated with neurotoxic effects and respiratory effects [Chmielewski and Renke, 1975; Brigham and Landrigan, 1985; Moscato et al, 1987; Kolstad et al, 1995]. Notably, there are recent case reports of obliterative bronchiolitis in England and Taiwan in the fiberglass boat and water tank industries, which share similar exposures with fiberglass windblade manufacture [Chen et al, 2013; Cullinan et al, 2013].…”

Section: Introductionmentioning

confidence: 99%

Styrene‐associated health outcomes at a windblade manufacturing plant

McCague

Cox‐Ganser

Harney

et al. 2015

American J Industrial Med

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Background Health risks of using styrene to manufacture windblades for the green energy sector are unknown. Methods Using data collected from 355 (73%) current windblade workers and regression analysis, we investigated associations between health outcomes and styrene exposure estimates derived from urinary styrene metabolites. Results The median current styrene exposure was 53.6 mg/g creatinine (interquartile range: 19.5–94.4). Color blindness in men and women (standardized morbidity ratios 2.3 and 16.6, respectively) was not associated with exposure estimates, but was the type previously reported with styrene. Visual contrast sensitivity decreased and chest tightness increased (odds ratio 2.9) with increasing current exposure. Decreases in spirometric parameters and FeNO, and increases in the odds of wheeze and asthma-like symptoms (odds ratios 1.3 and 1.2, respectively) occurred with increasing cumulative exposure. Conclusions Despite styrene exposures below the recommended 400 mg/g creatinine, visual and respiratory effects indicate the need for additional preventative measures in this industry.

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“…The effect of air pollutants produced by welding processes on the health of laborers, specifically welders, is a major concern of occupational medicine. − In addition to work-related injuries, welders often suffer from acute and chronic occupational diseases such as hepatitis, dermatitis, neuropathy, and encephalopathy and are often associated with respiratory conditions such as chronic obstructive pulmonary disease, asthma, chronic bronchitis, and pneumonia after long-term exposure. − Welders are also associated with an increased risk for lung cancer, laryngeal cancer, esophageal cancer, and, potentially, leukemia. − …”

Section: Introductionmentioning

confidence: 99%

Metabolomic Characterization of Laborers Exposed to Welding Fumes

Kuo

Wang

Tian

et al. 2012

Chem. Res. Toxicol.

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The complex composition of welding fumes, multiplicity of molecular targets, diverse cellular effects, and lifestyles associated with laborers vastly complicate the assessment of welding fume exposure. The urinary metabolomic profiles of 35 male welders and 16 male office workers at a Taiwanese shipyard were characterized via (1)H NMR spectroscopy and pattern recognition methods. Blood samples for the same 51 individuals were also collected, and the expression levels of the cytokines and other inflammatory markers were examined. This study dichotomized the welding exposure variable into high (welders) versus low (office workers) exposures to examine the differences of continuous outcome markers-metabolites and inflammatory markers-between the two groups. Fume particle assessments showed that welders were exposed to different concentrations of chromium, nickel, and manganese particles. Multivariate statistical analysis of urinary metabolomic patterns showed higher levels of glycine, taurine, betaine/TMAO, serine, S-sulfocysteine, hippurate, gluconate, creatinine, and acetone and lower levels of creatine among welders, while only TNF-α was significantly associated with welding fume exposure among all cytokines and other inflammatory markers measured. Of the identified metabolites, the higher levels of glycine, taurine, and betaine among welders were suspected to play some roles in modulating inflammatory and oxidative tissue injury processes. In this metabolomics experiment, we also discovered that the association of the identified metabolites with welding exposure was confounded by smoking, but not with drinking, which is a finding consistent with known modified response of inflammatory markers among smokers. Our results correspond with prior studies that utilized nonmetabolomic analytical techniques and suggest that the metabolomic profiling is an efficient method to characterize the overall effect of welding fume exposure and other confounders.

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Safety and health in boatbuilding and repair

Cited by 22 publications

References 14 publications

Work-related deaths in construction painting.

Work-related deaths in construction painting.

Styrene‐associated health outcomes at a windblade manufacturing plant

Metabolomic Characterization of Laborers Exposed to Welding Fumes

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