Safety and Utility of Mediastinoscopy in Non-Small Cell Lung Cancer in a Complex Mediastinum

Endobronchial Ultrasound–Guided Transbronchial Needle Aspiration for the Diagnosis and Subtyping of Lymphoma

“…A median of five needle passes were performed per lymph node (range, [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19]. There was no difference in the number of passes between patients with and without lymphoma (p=0.27).…”

“…5 In patients who present with intrathoracic adenopathy that is suspicious for lymphoma, endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an attractive option, given the risks of surgical or core needle sampling. 6,7 In such patients, EBUS-TBNA may be also useful for excluding alternative diagnoses, such as sarcoidosis, and help to identify patients who require more invasive tissue sampling. 8,9 The diagnostic utility of EBUS-TBNA in lung cancer diagnosis and staging, including biomarker analysis, has been well established.…”

Transbronchial and transesophageal fine-needle aspiration using a single ultrasound bronchoscope in the diagnosis of locoregional recurrence of surgically-treated lung cancer

“…However, few studies have focused on the role of mediastinoscopy in the diagnosis of locoregional recurrence. The concept of “complex” mediastinum refers to an altered fibrotic mediastinum secondary to previous thoracic surgery (primary mediastinoscopy or nodal dissection) or induction therapy [ 24 ]. Although some studies performed by expert surgeons in referral hospitals have shown good accuracy of remediastinoscopy, with complication rates similar to primary mediastinoscopy [ 25 ], remediastinoscopy is not widely used due to concerns about safety and usefulness [ 26 ].…”

Something borrowed, something blue: A gift for the bride with everything, including an ectopic parathyroid adenoma

“…6 Whereas mediastinoscopy can be performed safely by experienced surgeons after induction chemoradiation for lung cancer, complications, including azygous and recurrent nerve injuries, are more common. 7 Experience with mediastinoscopy in complex cases is also decreasing among thoracic trainees with increasing use of endobronchial ultrasound, and the open approach taken here is reasonable with a history of mantle radiation.…”