2011
DOI: 10.1111/j.1540-8159.2011.03260.x
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Safety Aspects of Deep Sedation during Catheter Ablation of Atrial Fibrillation

Abstract: Unconscious sedation with propofol and midazolam in AF ablation procedures lasting 3-5 hours did not result in severe changes of vital parameters or serum electrolytes. Anesthesia-associated problems were not observed. Propofol and midazolam can be safely used during catheter ablation of AF.

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Cited by 37 publications
(32 citation statements)
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“…Haemodynamic and oxygenation changes during anaesthesia stayed within the ranges of previous studies [15]. No case of severe or prolonged haemodynamic or respiratory instability due to sedation occurred.…”
Section: Resultssupporting
confidence: 73%
See 1 more Smart Citation
“…Haemodynamic and oxygenation changes during anaesthesia stayed within the ranges of previous studies [15]. No case of severe or prolonged haemodynamic or respiratory instability due to sedation occurred.…”
Section: Resultssupporting
confidence: 73%
“…Procedures were performed as described previously [15]. Patients were in a fasting state, and transoesophageal echocardiography was performed prior to the ablation to rule out a left atrial thrombus.…”
Section: Methodsmentioning
confidence: 99%
“…However, heart movement and desaturation caused by unstable respiration with considerable respiratory variations and airway obstruction due to a retracted tongue root are the main problems during the procedure. To avoid these issues, some studies recommended assisted ventilation or an anesthetist in immediate attendance during the procedures [6], [17], [18], [19]. However, these services require money, time, and the support of an anesthesiologist, and not all institutions can afford these preparations.…”
Section: Discussionmentioning
confidence: 99%
“…Nevertheless, the degree of pain relief for patients with AF undergoing RFA depends on the practices of each hospital's electrophysiology centre. Both general anaesthesia and conscious sedation are used (Carnlof, Insulander, & Jensen-Urstad, 2014;Norgaard et al, 2013;Wutzler et al, 2012).The European Association for Palliative Care suggested Oxycodone as one alternative to morphine in 2001, but at the time, in many countries, Oxycodone was still considered as a step II opioid, or as a constituent of compound preparations with a non-opioid analgesic. Since that time, use of Oxycodone has increased significantly in many countries and it has become one of the most prescribed opioids in the United States (King, Reid, Forbes, & Hanks, 2011).…”
Section: Introductionmentioning
confidence: 99%
“…Combinations of oxycodone and Paracetamol have a double central analgesic mechanism of action and induce rapid pain relief (Gatti et al, 2010). No gold standard exists for conscious pain management during RFA in patients with AF, but some studies have assessed deep sedation with propofol in patients undergoing RFA for AF (Wutzler et al, 2012).…”
Section: Introductionmentioning
confidence: 99%