Safety assessment of GM plants: An updated review of the scientific literature

Domingo, José L.

doi:10.1016/j.fct.2016.06.013

Cited by 89 publications

(43 citation statements)

References 57 publications

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“…However, Koch et al (2015) mentioned that such a result could be due to spore components other than Cry proteins. Domingo (2016) stated that with only a few exceptions, the reported studies in the last 6 years showed rather similar conclusions; the assessed GM soybeans, corn, rice, and wheat would be as safe as the parental species of these plants. However, in spite of the notable increase in the available information, studies on the long-term health effects of GM plants, including tests of mutagenicity, teratogenicity, and carcinogenicity seem to be still clearly necessary.…”

Section: World Controversysupporting

confidence: 50%

Genetically engineered (modified) crops (Bacillus thuringiensis crops) and the world controversy on their safety

Abbas¹

2018

Egypt J Biol Pest Control

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Bacillus thuringiensis (Bt) crops are plants genetically engineered (modified) to contain the endospore (or crystal) toxins of the bacterium, Bt to be resistant to certain insect pests. In 1995, the Environmental Protection Agency (EPA) in USA approved the commercial production and distribution of the Bt crops: corn, cotton, potato, and tobacco. Currently, the most common Bt crops are corn and cotton. The crystal, referred to as Cry toxins, is proteins formed during sporulation of some Bt strains and aggregate to form crystals. Such Cry toxins are toxic to specific species of insects belongs to orders: Lepidoptera, Coleoptera, Hymenoptera, Diptera, and Nematoda. In 2016, the total world area cultivated with genetically modified crops (GM crops) reached about 185 million ha. This review shows that there is a worldwide controversy about the safety of Bt crops to the environment and mammals. Some researchers support the cultivation of Bt crops depending upon the results of their laboratory and field studies on the safety of such crops. Others, however, are against Bt crops as they may cause risk to human.

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Section: World Controversysupporting

confidence: 50%

Genetically engineered (modified) crops (Bacillus thuringiensis crops) and the world controversy on their safety

Abbas¹

2018

Egypt J Biol Pest Control

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“…Animal feeding studies may provide additional and useful information to complement safety assessment of whole GM foods and feed, especially when unintended effects are suspected (Delaney, 2007). Long-term experiment and multiple generations' assessment besides the subchronic toxicity experiment and acute toxicity experiment were necessary for description of its safety in order to guarantee that the consumption of GM plant does not mean any health risk for the consumers (Domingo, 2016).…”

Section: Discussionmentioning

confidence: 99%

“…Once the GM food are commercialized, they will be consumed by people of various ages, sexes and health conditions for a long-term or even a life time (Dona and Arvanitoyannis, 2009), and will be also consumed in generations. Domingo (2016) considered that each GM product should be assessed with appropriate studies that indicate the level of safety associated with them. Therefore rigorous scientific safety assessment using strict procedures must be taken before commercialization.…”

Section: Discussionmentioning

confidence: 99%

Three-generation reproduction toxicity study of genetically modified rice with insect resistant genes

Yichun

Zhuo

Gong

et al. 2017

Food and Chemical Toxicology

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“…Scientific opinions claiming the safety of current (first generation) agricultural biotechnology (GM) products and urging their application (Barrows et al 2014;Domingo 2016) confront others claiming lack of evidence on their safety (Hilbeck et al 2015;Krimsky 2015), and exaggeration of what risk assessment can demonstrate as so-called ''lack of harm''. Both positions were considered in the latest evaluation by the US National Academy of Sciences (US NAS 2016).…”

Section: Environmental and Ecological Aspects In The Overall…mentioning

confidence: 99%

Environmental and Ecological Aspects in the Overall Assessment of Bioeconomy

Székacs

2017

J Agric Environ Ethics

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Bioeconomy solutions potentially reduce the utilization demand of natural resources, and therefore, represent steps towards circular economy, but are not per se equivalent to sustainability. Thus, production may remain to be achieved against losses in natural resources or at other environmental costs, and materials produced by bioeconomy are not necessarily biodegradable. As a consequence, the assumption that emerging bioeconomy by itself provides an environmentally sustainable economy is not justified, as technologies do not necessarily become sustainable merely through their conversion to using renewable resources for their production. A source of the above assumption is that the utility of bioeconomy is mostly assessed in interaction between technology developers and economists, resulting in biased assessment with private commercial technology benefits being included, but environmental costs, especially longer term ones, not being sufficiently considered in the economic models. A possible solution to this conceptual contradiction may come from bioethics, as a strong concept in environmental ethics is that no technological intervention can be imposed on nature beyond its receptive capacity. To achieve a better balanced analysis of bioeconomy, environmental and ecological, as well as non-economic social aspects, need to be included in the overall assessment.

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Safety assessment of GM plants: An updated review of the scientific literature

Cited by 89 publications

References 57 publications

Genetically engineered (modified) crops (Bacillus thuringiensis crops) and the world controversy on their safety

Genetically engineered (modified) crops (Bacillus thuringiensis crops) and the world controversy on their safety

Three-generation reproduction toxicity study of genetically modified rice with insect resistant genes

Environmental and Ecological Aspects in the Overall Assessment of Bioeconomy

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