Artificial intelligence (AI)—the field of computer science that designs machines to perform tasks that typically require human intelligence—has seen rapid advances in the development of foundation systems such as large language models. In the workplace, the adoption of AI technologies can result in a broad range of hazards and risks to workers, as illustrated by the recent growth in industrial robotics and algorithmic management. Sources of risk from deployment of AI technologies across society and in the workplace have led to numerous government and private sector guidelines that propose principles governing the design and use of trustworthy and ethical AI. As AI capabilities become integrated in devices, machines, and systems across industry sectors, employers, workers, and occupational safety and health practitioners will be challenged to manage AI risks to worker health, safety, and well‐being. Five risk management options are presented as ways to assure that only trustworthy and ethical AI enables workplace devices, machinery, and processes. AI technologies will play a significant role in the future of work. The occupational safety and health practice and research communities need to ensure that the promise of these new AI technologies results in benefit, not harm, to workers.