2023
DOI: 10.3390/pharmaceutics15020591
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Safety in Rats of a Novel Nasal Spray Formulation for the Prevention of Airborne Viral Infections

Abstract: Hexedra+® is a nasal spray containing hydroxypropyl methylcellulose, beta-cyclodextrin, and usnic acid. It has been developed with the aim of reducing the risk of transmission of airborne viral infections, with particular reference to influenza and COVID-19. As part of the preclinical development of the product, we carried out a study on thirty male Wistar rats divided into three study groups and treated with Hexedra+, an alternative formulation containing a double concentration of usnic acid (0.015% instead o… Show more

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