Safety of beta-alanine supplementation in humans: a narrative review

Oliveira, Erick P. de; Artioli, Guilherme Giannini; Burini, Roberto Carlos

doi:10.1007/s11332-023-01052-0

Cited by 1 publication

(1 citation statement)

References 57 publications

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“…The safety of isolated PWS components like creatine [ 68 ], β-alanine [ 69 ], citrulline [ 47 ], caffeine [ 70 ], and amino acids [ 71 ] has been well investigated. Some ingredients included in the present study on PWSs, such as creatine and BCAA, have been found to decrease muscle damage markers.…”

Section: Discussionmentioning

confidence: 99%

Effects of Four Weeks of In-Season Pre-Workout Supplementation on Performance, Body Composition, Muscle Damage, and Health-Related Markers in Basketball Players: A Randomized Controlled Study

Douligeris,

Methenitis,

Stavropoulos-Kalinoglou

et al. 2024

JFMK

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This randomized, double-blinded, experimental study investigated the effects of a four-week daily pre-workout supplementation (200 mg caffeine, 3.3 g creatine monohydrate, 3.2 g β-alanine, 6 g citrulline malate, and 5 g BCAA) vs. placebo (isocaloric maltodextrin) on anaerobic (jumping, sprinting, agility, and the running-based anaerobic sprint test: RAST) and aerobic (Yo-Yo intermittent recovery test level 1) performance, as well as on body composition and selective muscle damage/health-related blood markers in well-trained basketball players during the in-season period. Eighteen basketball players (age: 24.4 ± 6.3 years, height: 185.7 ± 8.0 cm, weight: 85.7 ± 12.8 kg, body fat: 16.5 ± 4.2%) were randomly assigned into two groups: pre-workout supplement (PWS, n = 10) or placebo (PL, n = 8). PWS consumption increased aerobic performance (PWS: 8 ± 6%; PL: −2 ± 6%; p = 0.004) compared to PL. A significant decrease was observed in peak (F = 7.0; p = 0.017), average (F = 10.7; p = 0.005), and minimum power (F = 5.1; p = 0.039) following 4 weeks of supplementation in both groups. No other significant changes were observed between groups (p > 0.05). In conclusion, the consumption of the current PWS over a four-week period appears to positively influence the aerobic performance of well-trained basketball players during the in-season period. However, it does not appear to mitigate the observed decline in anaerobic power, nor does it affect performance in jumping, sprinting, and agility, or alter body composition or selective muscle damage/health-related blood markers.

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