Safety of buquinolate in poultry and small animals*1

Effect of Buquinolate on Growth and Egg Production of White Leghorn Pullets

“…These estimates were compared with the regression of testcross progeny on inbred parent means in order to determine the efficacy of predicting inbred line mean performance in topcross combination. daily for 30 days were not affected (Borgmann et al, 1966). In contrast, for those traits with a high proportion of specific combining ability variance, e.g., percent adult mortality and age at first egg, the means of the inbred lines per se did not provide an efficient estimate of the inbreds in topcross combination.…”

Buquinolate—A Review

“…Toxicity-Buquinolate's toxicity is low in mice, rats, dogs, chickens, and turkeys (Borgmann et al, 1967). For example, the highest single oral doses tested-20 gm.…”

“…Chicks receiving buquinolate at 0.088 percent (over 10 times the recommended use level) in feed for 31 days, 0.044 percent (over 5 times the recommended level) for 10 weeks (Borgmann et al, 1967), and 0.066 percent (over 8 times the recommended level) for 9 weeks (Morrison, 1966) showed no signs of toxicosis. No signs of toxicosis appeared in rats fed the drug at 0.8 percent of the ration for 90 days.…”

Effect of Buquinolate on Broiler Chicks in Floor Pen Trials

“…It is relatively nontoxic, for it produced no signs of toxicosis when fed to broiler chickens from 1 day to 31 days of age at levels of 0.088% (Borgmann et al, 1966). Hematologic and blood chemical values were normal and microscopic examination of tissues and organs revealed no morphologic changes that could be attributed to drug action.…”