Safety of calcitonin stimulation tests with calcium

Băetu, Mara; Olariu, Cristina; Nitu, Ileana; Moldoveanu, Gabriel; Cristina, Carolina; Badiu, Corin

doi:10.1007/s42000-021-00315-0

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…Although other factors have been described as stimulating calcitonin secretion, pentagastrin (mainly) and the administration of venous calcium are true secretagogues, being important agents for the clinical evaluation of calcitonin secretion by normal and neoplastic cells (Wondisford, 2020;Wong, Nabata, & Wiseman, 2022). Some authors suggested that calcitonin is also responsible for the alteration of the postoperative calcium concentration in thyroidectomies (Băetu, Olariu, Nițu, et al, 2021;Băetu, Olariu, Stancu, et al, 2021;Tausanovic et al, 2021). Manipulation of the thyroid gland would lead to an increase in calcitonin secretion and, consequently, to a decline in calcium.…”

Section: Calcitoninmentioning

confidence: 99%

Post-thyroidectomy hypocalcemia and related complications

Al-Roubaie

2022

ijhs

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The incidence of post-thyroidectomy hypocalcemia is high while the factors involved include age (> 50 years), type of operation, operative time, neck dissection, histology of the surgical specimen and vocal fold paralysis. Low ionic calcium concentrations are indicative of the presence of symptoms of hypocalcemia and the need for oral calcium. Progression to definitive hypoparathyroidism occurs only in patients with clinical manifestations of post-thyroidectomy hypocalcemia. In general, the problem with post-surgical hypoparathyroidism resides in the surgical procedure itself. The most common are related to neuronal hyperexcitability, which explains the paresthesias, cramps and numbness, which usually start in the perioral region and on the fingertips. Muscle spasms and muscle stiffness are also common. When severe, hypocalcemia can lead to life-threatening spastic tetany, laryngospasm, and seizures. The current manuscript aimed to present a review of the bibliography on thyroidectomy and negative impact of its complications on human health, mainly because of a higher risk for developing hypocalcemia. To achieve the study goal, this review covered most recent published articles from 2017 onward.

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