2020
DOI: 10.1111/bcp.14552
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Safety of clonidine used for long‐term sedation in paediatric intensive care: A systematic review

Abstract: Aim Although not approved, the α‐adrenoceptor agonist clonidine is considered an option for long‐term sedation protocols in paediatric intensive care. We reviewed adverse effects of clonidine occurring in this indication. Methods Relevant literature was systematically identified from PubMed and Embase. We included interventional and observational studies on paediatric patients admitted to intensive care units and systemically long‐term sedated with clonidine‐containing regimes. In duplicates, we conducted stan… Show more

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Cited by 4 publications
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References 72 publications
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