Safety of complementary medicines should be monitored

“…Another Chinese herb is Dictamnus dasycarpus, which has been used for treating skin diseases (127). Few reports reported hepatotoxic events and death associated with consumption D. dasycarpus with other herbal preparation (128,129,130,131). Additionally, Kampo medicine including DaiSaiko-to and Syo-saiko-to consists of mixture of herbs that has been used as a remedy of several illnesses like dyspepsia and pyretic diseases (10,133).…”

Section: Discussionmentioning

confidence: 99%

“…It belongs to Rutaceae family and has been used as a remedy for skin diseases, cough, jaundice and rheumatism (127). D. dasycarpus has been linked with some hepatotoxic events as well as death (10,128,129,130,131). One case of hepatic injury involved a 49-year-old female presented with itching and jaundice after drinking a mixture of Chinese herbal tea for her eczematous skin disease.…”

Section: Chinese Herbal Remediesmentioning

confidence: 99%

Hepatotoxic Botanicals - An Evidence-based Systematic Review

Abdualmjid

Sergi

2013

J Pharm Pharm Sci

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-Purpose. Herbal medicines have been increasingly used worldwide. However, the potential harms of these herbs have been noticed most recently following hepatotoxicity with ingestion of herbal remedies. The aim of this review is to evaluate the evidence of hepatotoxic effects linked to use of herbal preparations. Method. Electronic search was performed by searching several databases: PubMed, HerbMed, Google Scholar, Scopus, Cochrane Database of Systematic Reviews and Cochrane Library using both Latin and common names of several herbs. Language was restricted to English and articles were selected for relevance reporting incidence of hepatotoxicity associated with use of herbal products in human. Results. From a total of 565 relevant reviews and articles, 254 met our inclusion criteria and were analyzed.

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“…For example, a "dietary supplement" (LipoKinetix [Syndtrax, Cape Girardeau, MO]), a combination product sold for weight loss containing both herbals (yohimbine and usinate) and non-herbals, was associated with fulminant hepatic failure [17]. Chinese herbals, in combination and some with unknown ingredients, have been associated with hepatitis and fulminant hepatic failure [18][19][20].…”

Section: Herbals As Drugsmentioning

confidence: 98%

Herbal supplements

Lipman¹

2005

Curr Gastroenterol Rep

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Herbal dietary supplements are taken by many individuals, often without the knowledge of their clinicians. Herbals have many pharmacologic and medicinal properties but are unregulated with respect to manufacturing purity, safety, and efficacy. Although clinicians often dismiss the utility of herbal therapy, many randomized controlled trials of herbal use in gastrointestinal and liver diseases have been conducted. There is no evidence for benefit from herbal supplements in the treatment of liver disease, but sufficient evidence exists for their use in functional gastrointestinal symptoms to warrant further investigation.

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Safety of complementary medicines should be monitored

Cited by 36 publications

References 3 publications

The Use of Selected Nutrition Supplements and Complementary and Alternative Medicine in Liver Disease

The Use of Selected Nutrition Supplements and Complementary and Alternative Medicine in Liver Disease

Hepatotoxic Botanicals - An Evidence-based Systematic Review

Herbal supplements

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