Safety of drugs used in cases with ulcerative colitis during pregnancy and lactation

Kalkan, İsmail Hakkı; Dağlı, Ülkü

doi:10.4318/tjg.2012.0624

Turk J Gastroenterol

2012

DOI: 10.4318/tjg.2012.0624

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Safety of drugs used in cases with ulcerative colitis during pregnancy and lactation

İsmail Hakkı Kalkan¹,

Ülkü Dağlı²

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2020

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“…We safely performed endoscopy in patients with suspected disease exacerbation. 5-ASA compounds and corticosteroids commonly used are very safe for use in IBD treatment during pregnancy(24). No association of combination therapy with a higher risk for spontaneous abortion, low birth weight, congenital abnormalities, and cesarean section was confirmed with the data from the Pregnancy in Inflammatory Bowel Disease and Neonatal Outcomes (PIANO) registry(25).Boyd HA et al have found that women with IBD are at increased risk of significant congenital malformations.…”

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confidence: 96%

İnflamatuar bağırsak hastalığı olan gebelerin klinik yönetimi ve sonuçları

Aydın¹,

Tolunay²,

Boza³

et al. 2020

Türk Kadın Sağlığı Ve Neonatoloji Dergisi

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Aim: Inflammatory bowel diseases (IBD); ulcerative colitis (UC) and Crohn's disease (CD) are chronic pathologies affecting young adults. Pregnancy and IBD are multidimensional and could be affected by many variables. In this study, we aimed to present our pregnants with IBD, and their clinical management and pregnancy outcomes. Material and method: Pregnants with IBD were retrospectively evaluated and grouped as those with UC and CD. A total of nine cases were included in this study. Results: The mean age of the patients was 28.5 ± 4.9 years. The mean gravida and parity numbers were 2.6 ± 1 and 1.55 ± 1.13 respectively. Six patients with IBD had UC, and three patients had CD. Two patients were newly diagnosed, and seven patients had a history of IBD. The mean gestational week of the eight patients was 34.2 ± 4.55 weeks. The mean birth weight, and first and fifth minute APGAR scores of the eight patients were 2530 ± 956 gr, 7.6 ± 0.91 and 8.87 ± 0.83, respectively (n=8). Conclusion: IBD affects a large group of women of childbearing age. Pregnancy, maternal and fetal outcomes are widely affected by disease activity. Becoming pregnant can be advised if the disease is quiescent, with rapid and efficient management of possible flare-ups. Controlling IBD is the main factor for obstetrical prognosis in pregnancy.

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mentioning

confidence: 96%

İnflamatuar bağırsak hastalığı olan gebelerin klinik yönetimi ve sonuçları

Aydın¹,

Tolunay²,

Boza³

et al. 2020

Türk Kadın Sağlığı Ve Neonatoloji Dergisi

View full text Add to dashboard Cite

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Safety of drugs used in cases with ulcerative colitis during pregnancy and lactation

Cited by 1 publication

References 66 publications

İnflamatuar bağırsak hastalığı olan gebelerin klinik yönetimi ve sonuçları

İnflamatuar bağırsak hastalığı olan gebelerin klinik yönetimi ve sonuçları

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