Safety of inadvertent administration of overdose of intrathecal Cytarabine in a pediatric patient

Abstract

Supportive care without the need for invasive procedures such as cerebrospinal fluid exchange may be adequate for managing intrathecal Cytarabine overdose.

Safe Administration of Intracerebral Spinal Fluid Chemotherapy: Time for Guidelines

“…Since 1968, more than 69 cases of ICC administration errors have been documented. [7][8][9][10][11] However, the incidence is likely higher due to under-reporting. Most reported errors have been inadvertent ICC administration of an injection intended to be parenterally administered, including bortezomib, doxorubicin, daunorubicin, dactinomycin, videsine, and vincristine.…”