2011
DOI: 10.4081/reumatismo.2006.261
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Safety of methotrexate in rheumatoid arthritis: a retrospective cohort study in clinical practice

Abstract: Objective. To evaluate the treatment duration with MTX monotherapy or in association with DMARDs or anti TNFa inhibitors and the incidence and typology of adverse events (AE) occurred in rheumatoid arthritis (RA) patients. Methods. A retrospective large cohort study of RA outpatients, consecutively seen from January 2000 to June 2005 was performed. Study group were RA patients classified according to the 1984 ACR criteria for the classification of rheumatoid arthritis. The patients were divided in 3 groups acc… Show more

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