Safety of sulfadoxine/pyrimethamine for intermittent preventive treatment of malaria in infants: evidence from large-scale operational research in southern Tanzania

Maokola, Werner; Chemba, Mwajuma; Hamisi, Yuna; Mrisho, Mwifadhi; Shirima, Kizito; Manzi, Fatuma; Masanja, M. Irene; Willey, Barbara; Alonso, Pedro L.; Mshinda, Hassan; Tanner, Marcel; Schellenberg, Joanna; Schellenberg, David

doi:10.1016/j.inhe.2011.03.009

Cited by 3 publications

(1 citation statement)

References 30 publications

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“…Examples include the SAFE (Surgery [for trichiasis]–Antibiotics–Facial cleanliness–Environmental improvement) strategy for trachoma, 38 expanding coverage of HAART, 39 – 41 evaluating pre-HAART, 42 evaluating surveillance for malaria elimination, 43 improving the management of HIV–TB coinfection, 44 evaluating cotrimoxazole preventive therapy, 45 improving the diagnosis and management of recurrent TB, 46 preventing mother-to-child transmission of HIV, 47 and the preventive treatment of malaria in infants. 48 In their paper on the concepts, contributions, and challenges on operational research, Zachariah et al provide 16 examples of how it has improved medical care and practice, been used to assess the feasibility of interventions, and been used to advocate policy change. 37 …”

Section: Impact Of Infectious Disease Research On Healthmentioning

confidence: 99%

Learning lessons from operational research in infectious diseases: can the same model be used for noncommunicable diseases in developing countries?

Bosu¹

2014

AMEP

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About three-quarters of global deaths from noncommunicable diseases (NCDs) occur in developing countries. Nearly a third of these deaths occur before the age of 60 years. These deaths are projected to increase, fueled by such factors as urbanization, nutrition transition, lifestyle changes, and aging. Despite this burden, there is a paucity of research on NCDs, due to the higher priority given to infectious disease research. Less than 10% of research on cardiovascular diseases comes from developing countries. This paper assesses what lessons from operational research on infectious diseases could be applied to NCDs. The lessons are drawn from the priority setting for research, integration of research into programs and routine service delivery, the use of routine data, rapid-assessment survey methods, modeling, chemoprophylaxis, and the translational process of findings into policy and practice. With the lines between infectious diseases and NCDs becoming blurred, it is justifiable to integrate the programs for the two disease groups wherever possible, eg, screening for diabetes in tuberculosis. Applying these lessons will require increased political will, research capacity, ownership, use of local expertise, and research funding.

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Section: Impact Of Infectious Disease Research On Healthmentioning

confidence: 99%

Learning lessons from operational research in infectious diseases: can the same model be used for noncommunicable diseases in developing countries?

Bosu¹

2014

AMEP

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When “Good Evidence” Is Not Enough: A Case of Global Malaria Policy Development

D'Souza

Parkhurst

2018

Global Challenges

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This paper presents findings from a case study of two different policy development processes within the WHO's malaria department. By comparing the policy processes for the interventions of intermittent preventive treatment in infants versus children, the findings suggest that “good evidence” from a technical perspective, though important, is not sufficient to ensure universal agreement and uptake of recommendations. An analysis of 29 key informant interviews finds that evidence also needs to be relevant to the policy question being asked, and that expert actors retain a concern over the legitimacy of the process by which technical evidence is brought to bear in the policy development process. Previous findings from the field of sustainable development, that evidence must be credible, salient, and legitimate to be accepted by the public, appears to apply equally within scientific advisory committees. While the WHO has principally focused on technical criteria for evidence inclusion in its policy development processes, this study suggests that the design and functionality of its advisory bodies must also enable transparent, responsive, and accepted processes of evidence review to ensure that these bodies are effective in producing advice that engenders change in policy and practice.

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Can Co-administration of Sulfadoxine-pyremathamine and Single-dose Activated Charcoal Reduce the Chances of Adverse Reactions in Cases of Inadvertent Repeat Dose?

Emeka¹

2016

International J. of Pharmacology

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Safety of sulfadoxine/pyrimethamine for intermittent preventive treatment of malaria in infants: evidence from large-scale operational research in southern Tanzania

Cited by 3 publications

References 30 publications

Learning lessons from operational research in infectious diseases: can the same model be used for noncommunicable diseases in developing countries?

Learning lessons from operational research in infectious diseases: can the same model be used for noncommunicable diseases in developing countries?

When “Good Evidence” Is Not Enough: A Case of Global Malaria Policy Development

Can Co-administration of Sulfadoxine-pyremathamine and Single-dose Activated Charcoal Reduce the Chances of Adverse Reactions in Cases of Inadvertent Repeat Dose?

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