Safety of uneventful cesarean section in terms of hemorrhage

Bodur, Serkan; Gün, İsmet; Özdamar, Özkan; Babayiğit, Mustafa Alparslan; Kıncı, Mehmet Ferdi

doi:10.1016/j.ejogrb.2016.07.171

Cited by 3 publications

(3 citation statements)

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“…Postpartum hemorrhage (PPH) is one of most common diseases of maternal death worldwide and severe morbidity during pregnancy [1]. Uterine atony, injury of birth canal, abnormal placenta, and dysfunction of blood coagulation were the leading cause of PPH in pregnant women with cesarean section, and the average blood loss during cesarean section is significantly higher than that during vaginal delivery [2, 3]. Currently, western medicine such as oxytocin [4], carboprost tromethamine [5], and misoprostol [6] can play an important role in addressing the issue of PPH during and after cesarean section.…”

Section: Introductionmentioning

confidence: 99%

Traditional Chinese Medicine Yimucao Injection Combined with Western Medicine for Preventing Postpartum Hemorrhage after Cesarean Section: A Systematic Review and Meta-Analysis

Chen

Xie

Tian

et al. 2019

Evidence-Based Complementary and Alternative Medicine

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Objective. Yimucao injection combined with several contraction uterus drugs is in use for preventing postpartum hemorrhage after cesarean section. The present study is a meta-analysis comparing the efficacy and safety of these drugs. Methods. PubMed, Cochrane Library, Embase, the China National Knowledge Infrastructure (CNKI), the Chinese Biomedical Database (CBM), VIP, and Wanfang database were searched until June 2018. We selected RCTs of Yimucao injection combined with western medicine for preventing postpartum hemorrhage and study quality was assessed using the revised Cochrane risk of bias tool. Forty-eight RCTs are comprised of 7,330 participants. Results. The overall response rate of Yimucao injection combined with western medicine as a class (OR=4.19, 95%CI=2.83, 6.20, P<0.00001) was found to be significantly improved than western medicine alone. Yimucao injection combined with western medicine group could significantly reduce blood loss in intraoperative (SMD= -1.15, 95%CI= -1.43, -0.87, P<0.00001), compared with control group. The treatment group could significantly reduce postpartum blood loss within 2 hours (SMD= -1.73, 95%CI= -2.01, -1.46, P<0.00001) and had a significantly lower blood loss within 24 hours (SMD= -1.92, 95%CI= -2.21, -1.63, P<0.00001) than control group. Additionally, in terms of the safety, Yimucao injection group reduced the risk of adverse events in the course of prevention than the western medicine group. Conclusions. This study demonstrated that Yimucao injection combined with western medicine may be more effective for preventing postpartum hemorrhage after cesarean section. However, high-quality and large multicenter randomized clinical trials will be needed to prove the consequence in the further.

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Section: Introductionmentioning

confidence: 99%

Traditional Chinese Medicine Yimucao Injection Combined with Western Medicine for Preventing Postpartum Hemorrhage after Cesarean Section: A Systematic Review and Meta-Analysis

Chen

Xie

Tian

et al. 2019

Evidence-Based Complementary and Alternative Medicine

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“…Transfüzyon gereksinimi, maternal taşikardi (>110 atım /dk), baş dönmesi, mobilizasyon güçlüğü gibi hastanın klinik durumları ve hematokrit değerlerindeki farkın %20'den fazla olmasına göre konulmuştur(9). 'sine kan transfüzyonu yapılmışken, sezaryen doğum yapılan grupta kan transfüzyonu ihtiyacı olmamıştır (%0)(Tablo 2).…”

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Vakum Yardimli Doğum: Neden Çeki̇ni̇yoruz?

Fidan

Ulubay

Kıncı

et al. 2018

Kocatepe Tıp Dergisi

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“…It is contributing to about 25% of direct maternal deaths [2]. The incidence of PPH is about 1.2% [3]. Conservative treatment of PPH includes uterine massage, uterotonics, uterine packing, pelvic vessel ligation, uterine compression suture and uterine artery embolization [4].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Subendometrial and Intramyometrial Blood Flow after Intravenous Tranexamic Acid for Prevention of Postpartum Hemorrhage in Vaginal Delivery: A Randomized Controlled Study

Ismail¹,

Abbas²,

Shahat³

et al. 2017

J Gynecol Res Obstet

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Objective: The study aims to test the effect of tranexamic acid (TA) on uterine vasculature and blood loss after vaginal delivery. Materials and methods:A randomized, double-blind, placebo-controlled trial, conducted in Assiut Woman's Health Hospital, Egypt between the 1st of October 2015 and the 31st of March 2016 included pregnant women (37-42 weeks) with a single living cephalic fetus. The eligible women were randomized to receive TA or placebo after vaginal delivery. Doppler indices were measured for the subendometrial, intramyometrial and uterine blood vessels two hours after delivery. The main study outcome was the effect of TA on subendometrial and intramyometrial blood fl ow. Results:Two hundred women were enrolled (n=100 in each group). There was a signifi cant increase in the Doppler indices of subendometrial and intramyometrial blood vessels with no difference in indices in uterine arteries between both groups. The mean of estimated blood loss decreased signifi cantly in TA group (p<0.001). The haematocrit and hemoglobin levels were higher in TA group than the placebo group after delivery (p<0.001). Conclusions:The use of intravenous TA after vaginal delivery increases the resistance in the subendometrial and intramyometrial blood vessels and reduces postpartum hemorrhage.

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Safety of uneventful cesarean section in terms of hemorrhage

Cited by 3 publications

References 1 publication

Traditional Chinese Medicine Yimucao Injection Combined with Western Medicine for Preventing Postpartum Hemorrhage after Cesarean Section: A Systematic Review and Meta-Analysis

Traditional Chinese Medicine Yimucao Injection Combined with Western Medicine for Preventing Postpartum Hemorrhage after Cesarean Section: A Systematic Review and Meta-Analysis

Vakum Yardimli Doğum: Neden Çeki̇ni̇yoruz?

Evaluation of Subendometrial and Intramyometrial Blood Flow after Intravenous Tranexamic Acid for Prevention of Postpartum Hemorrhage in Vaginal Delivery: A Randomized Controlled Study

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