Safety surveillance and causality assessment of adverse event following immunization in children - A vaccine vigilance study

Deoja, Glory; Shanmuganathan, P.; Manimekalai, K

doi:10.5455/njppp.2018.8.0413530042018

Cited by 3 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Majority of the respondents in this study mentioned fever as the most experienced AEFI, which was corroborated by findings of other studies. [ 1 , 4 , 13 , 16 , 20 ] Other forms AEFI experienced in the study were pains and swelling as well as convulsion which were also in tandem with what was observed in another Nigerian study. [ 4 ] Appropriate actions following AEFI were taken by less than a quarter of the mothers in this study.…”

Section: Discussionsupporting

confidence: 69%

“…The prevalence of AEFI in this study was found to be higher than what was reported in studies conducted in India, Nigeria, Poland and Brazil respectively. [ 1 , 4 , 13 , 16 , 20 , 21 ] It is imperative to state that the variation in the prevalence of AEFI observed in studies across different countries could be attributable to the fact that the studies were conducted in different settings and level of health care services provision. Furthermore, self-reporting approach to assessment of the occurrence of AEFI was used in this which could have been improved on if a cohort of mothers were selected and followed up to actually determine the incidence of AEFI among their children.…”

Section: Discussionmentioning

confidence: 99%

“…Vaccination has been adjudged one of the most successful public health interventions globally which has achieved significant reduction in morbidity and mortality associated with vaccine preventable diseases. [ 1 , 2 ] Adverse Event Following Immunization (AEFI) refers to any unfavourable event occurring following vaccination related to the vaccine administration and or its handling. [ 2 – 7 ] AEFI can be categorized as vaccine reactions, program errors, coincidental events, injection reactions and unknown events .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Knowledge of adverse events following immunization, its prevalence and actions of mothers of children aged 0–23 months in a tertiary health institution in Jos, North Central Nigeria

et al. 2020

View full text Add to dashboard Cite

Background: Adverse Event Following Immunization (AEFI) is any unfavorable event occurring following vaccination related to the vaccine administration and or its handling. AEFI can lead to death or a life-threatening condition requiring hospitalization with or without permanent sequel. Hence, this study was conducted to determine the knowledge of AEFI among mothers of children aged 0–23 months, its prevalence and actions of mothers of following AEFIs. Methodology: This was a cross-sectional study conducted among 400 mothers of children aged 0–23 months between November 2017 and April 2018 using quantitative method of data collection. IBM SPSS version 20 was used for data analysis where chi square was used as a test of association a P -value of ≤ 0.05 considered statistically significant. Results: The mean age of the respondents in the study was 29.0 ±5.3 years with 222 (55.5%) demonstrating good knowledge of AEFI. The prevalence of AEFI was found to be 46.5% with fever as the most experienced AEFI accounting for 90.3% of all cases experienced followed by pain and swelling mentioned by 141 (75.8%) and 26 (14.0%) respectively. Only 26 (14.5) of the mothers were adjudged to have taken appropriate action following the experience of AEFI in their children. Appropriateness of actions taken by the mothers following the occurrence of AEFI was influenced by the mother’s employment status (COR= 3.84; 95% CI=1.366–10.575; P =0.007). Conclusion: This study has demonstrated a sub-optimal level of knowledge of AEFI among the mothers of children aged 0–23 months with a relatively high self-reported prevalence and poor level of appropriateness of actions taken following AEFI.

show abstract

Section: Discussionsupporting

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Knowledge of adverse events following immunization, its prevalence and actions of mothers of children aged 0–23 months in a tertiary health institution in Jos, North Central Nigeria

et al. 2020

View full text Add to dashboard Cite

show abstract

“…This finding is consistent with several other studies on AEFI, including one study published in 2018. 10 This is also consistent with other studies looking at adverse drug reactions and AEFI, in which administration and general disorders were predominant. 11,16 We also found that pyrexia, as a PT, was the predominant AEFI.…”

Section: Discussionsupporting

confidence: 90%

Adverse Events Following Immunization with Novel Oral Polio Vaccine Type 2, and the Experience and Challenges of Reporting in Sierra Leone

Thomas,

Abiri,

Kallon

et al. 2024

DHPS

View full text Add to dashboard Cite

“…Vaccination has been adjudged one of the most successful public health interventions globally, which has achieved a significant reduction in morbidity and mortality associated with vaccine-preventable diseases [1]. Childhood immunization is one interventions that has promoted the health, well-being, and survival of children [2].…”

Section: Introductionmentioning

confidence: 99%

Predictors of Adverse Events Following Immunization Reporting amongst Healthcare Workers in Jigawa State, Northern Nigeria, 2022

Uba¹

2023

TIJPH

View full text Add to dashboard Cite

An adverse event following immunization (AEFI) is any untoward medical occurrence that follows immunization and does not necessarily have a causal relationship with the usage of the vaccine. Reporting of AEFI is suboptimal amongst healthcare workers (HWs). This study aimed to determine predictors of HW’s reporting of AEFI. A descriptive cross-sectional study was conducted among HWs in selected health facilities (HFs) in Jigawa State using an open data kit self-administered questionnaire to collect data on socio-demographic characteristics, training, knowledge, and their practices on AEFI reporting. Analysis was conducted using Statistical Package for Social Sciences (SPSS) for frequencies, proportions, and associations using bivariate analysis and multivariate analysis using logistic regression to determine predictors of AEFI reporting with statistical significance set at p<0.05 and 95% confidence interval. Of the 400 respondents, 280 (70%) respondents had good knowledge of AEFI, 328(82%) sends routine AEFI reports and of 212 (53%) who recently encountered an AEFI, 174 (82.1%) exhibited some good reporting practices. Female gender (AOR 0.46, p=0.035), full-time employees (AOR 0.227, p=0.019), a recent encounter with an AEFI (AOR 3.087, p=0.007) and being trained on AEFI (AOR 5.54, p=0.011), reporting to elicit training (AOR 2.70, p=0.031) were predictors of routine reporting from health facility and reporting an encountered AEFI respectively. Overall, gender, employment status, being trained, and recent AEFI encounter to elicit training were predictors of AEFI reporting. To improve reporting of AEFI, there is a need to engage and train health workers on AEFI surveillance. Keywords: Adverse events following immunization, Knowledge, Practice, Predictors, Reporting.

show abstract

Safety surveillance and causality assessment of adverse event following immunization in children - A vaccine vigilance study

Cited by 3 publications

References 0 publications

Knowledge of adverse events following immunization, its prevalence and actions of mothers of children aged 0–23 months in a tertiary health institution in Jos, North Central Nigeria

Knowledge of adverse events following immunization, its prevalence and actions of mothers of children aged 0–23 months in a tertiary health institution in Jos, North Central Nigeria

Adverse Events Following Immunization with Novel Oral Polio Vaccine Type 2, and the Experience and Challenges of Reporting in Sierra Leone

Predictors of Adverse Events Following Immunization Reporting amongst Healthcare Workers in Jigawa State, Northern Nigeria, 2022

Contact Info

Product

Resources

About